Comparative Effects of Rupatadine 10 mg, Hydroxyzine 50 mg and Placebo on Actual Driving Performance
The primary objective of this study is to measure and compare the acute effects of rupatadine 10 mg, relative to placebo and hydroxyzine 50 mg as an active control on healthy volunteers’ performance on a standard over-the-road driving test and a car-following test.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety Study
Intervention Model: Crossover Assignment
Primary Purpose: Prevention
|Official Title:||Comparative Effects of Rupatadine 10 mg, Hydroxyzine 50 mg and Placebo on Actual Driving Performance|
- Actual driving performance
- Daytime sleepiness
- Subjective sleepiness
|Study Start Date:||May 2005|
|Estimated Study Completion Date:||November 2005|
The study shall be conducted according to a three-way, double-blind, placebo and active controlled crossover design. Treatment groups are identified as follows.
|Brain and Behaviour Institute|
|Maastricht, Netherlands, 6229 ET|
|Principal Investigator:||Erik Vuurman, PhD||Maastricht University, Brain and Behaviour Institute|