Prevalence of Proteinuria and Chronic Kidney Disease in Pediatric HIV-Infected Patients
This study has been completed.
Sponsor:
Children's Research Institute
Information provided by:
Children's Research Institute
ClinicalTrials.gov Identifier:
NCT00153621
First received: September 8, 2005
Last updated: May 2, 2008
Last verified: September 2005
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Purpose
Among adults with Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS), Chronic Kidney Disease (CKD) has previously been reported to occur in approximately 10% of children with HIV-infection. The frequency of CKD, its causes, and its natural history in children and adolescents with HIV-infection have not been systematically studied, particularly in the era of new anti-retroviral medications. The primary aim of this study is to determine the how common pediatric HIV-infected individuals have evidence of persistent proteinuria and CKD.
| Condition |
|---|
|
Chronic Kidney Failure AIDS-Associated Nephropathy HIV Infections |
| Study Type: | Observational |
| Study Design: | Time Perspective: Prospective |
| Official Title: | Prevalence of Proteinuria and Chronic Kidney Disease in Pediatric Patients in the Special Immunology, Burgess, and Nephrology Clinics |
Resource links provided by NLM:
Further study details as provided by Children's Research Institute:
| Estimated Enrollment: | 320 |
| Study Start Date: | September 2004 |
| Study Completion Date: | September 2007 |
Show Detailed Description Eligibility| Ages Eligible for Study: | 1 Year to 21 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Criteria
Inclusion Criteria:
- Known/confirmed HIV-infection or AIDS
- Age > 1 but < 21 years of age
- Able to tolerate discontinuation of ACEI or ARB
- Either gender
Exclusion Criteria:
- HIV negative status
- Age < 1 or > 21 years of age
- Unable to tolerate discontinuation of ACEI or ARB
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00153621
Locations
| United States, District of Columbia | |
| Children's National Medical Center | |
| Washington, District of Columbia, United States, 20010 | |
Sponsors and Collaborators
Children's Research Institute
Investigators
| Principal Investigator: | Kevin D. McBryde, MD | Children's Research Institute |
| Study Director: | Susan L. Furth, MD, PhD | Johns Hopkins University |
More Information
No publications provided
| ClinicalTrials.gov Identifier: | NCT00153621 History of Changes |
| Other Study ID Numbers: | 3406, NCRR 1K12RR017613-01 |
| Study First Received: | September 8, 2005 |
| Last Updated: | May 2, 2008 |
| Health Authority: | United States: Institutional Review Board |
Keywords provided by Children's Research Institute:
|
Pediatrics Chronic Kidney Failure HIV Acquired Immunodeficiency Syndrome AIDS-Associated Nephropathy |
Additional relevant MeSH terms:
|
Acquired Immunodeficiency Syndrome HIV Infections Kidney Diseases Kidney Failure, Chronic Proteinuria Renal Insufficiency AIDS-Associated Nephropathy Renal Insufficiency, Chronic Lentivirus Infections Retroviridae Infections RNA Virus Infections |
Virus Diseases Sexually Transmitted Diseases, Viral Sexually Transmitted Diseases Slow Virus Diseases Immunologic Deficiency Syndromes Immune System Diseases Urologic Diseases Urination Disorders Urological Manifestations Signs and Symptoms |
ClinicalTrials.gov processed this record on May 19, 2013