Prediction of Medication Compliance Following Renal Transplantation
The purpose of this study is to quantitate pre-transplant medication compliance, dialysis compliance, and related psychological variables, and then examine their validity as predictors of post-transplant noncompliant behaviors and clinically relevant outcomes (acute rejection, graft loss, or death).
Hypothesis: Noncompliance with pre-transplant medication or with the dialysis prescription, and specific psychological variables predict similarly noncompliant behaviors after transplantation.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Prediction of Medication Compliance Following Renal Transplantation|
- Prediction of early medication adherence [ Time Frame: 3 months ] [ Designated as safety issue: No ]Prediction of declining medication adherence during first three months post kidney transplantation.
|Study Start Date:||January 2003|
|Estimated Study Completion Date:||January 2015|
|Estimated Primary Completion Date:||January 2015 (Final data collection date for primary outcome measure)|
This pilot study is intended to provide preliminary data about the feasibility of recruiting a cohort of subjects on hemodialysis and following them prospectively through the transplant procedure. The study will document patient adherence to medications and treatment, both before and after surgery. These preliminary data will permit appropriate design and power calculations for a future study assessing our ability to predict post-transplant compliance, based on pre-transplant behaviors.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00148187
|Contact: Thomas E Nevins, MDfirstname.lastname@example.org|
|United States, Minnesota|
|University of Minnesota||Recruiting|
|Minneapolis, Minnesota, United States, 55455|
|Contact: Thomas E Nevins, MD 612-626-2922 email@example.com|
|Principal Investigator:||Thomas E Nevins, MD||University of Minnesota - Clinical and Translational Science Institute|