Cognitive Training in the Elderly

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2005 by Beersheva Mental Health Center.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Beersheva Mental Health Center
ClinicalTrials.gov Identifier:
NCT00146263
First received: September 4, 2005
Last updated: September 5, 2010
Last verified: September 2005
  Purpose

Background:

The aging of the population has lead to a significant increase in the number of older people suffering from cognitive impairment and dementia. The present lack of effective drug therapy for these conditions makes it imperative to investigate other potential therapeutic interventions.

Cognitive training has been described as possibly useful in improving cognitive function in elderly subjects with mild impairment and early dementia. However, there have been few well-designed studies to date and the results are equivocal. Most studies have relied on the use of paper-based neuropsychological assessment instruments with limited accuracy and reproducibility. The investigators have developed a validated computerized neuropsychological assessment battery with increased test-retest reliability.

The purpose of this study is to assess the efficacy of a computerized training program on cognitive function in older persons with normal cognition, mild cognitive impairment, and early dementia.

Description:

A randomized prospective AB/BA crossover study.

Methods:

Eligible males and females aged 60 years and older following initial computerized neuropsychological assessment will be randomized to receive either a 12-session computerized cognitive training program, or no treatment. Repeat neuropsychological assessment will be followed by a 4-week no treatment phase, reassessment and crossover phase. Repeat assessments will be performed at three and six months.


Condition Intervention
Dementia
Behavioral: computerized cognitive training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: The Effect of Computerized Cognitive Training on Neuropsychological Measures of Cognitive Function in the Elderly

Resource links provided by NLM:


Further study details as provided by Beersheva Mental Health Center:

Primary Outcome Measures:
  • changes in cognitive function

Estimated Enrollment: 300
Study Start Date: September 2005
Estimated Study Completion Date: June 2007
  Eligibility

Ages Eligible for Study:   60 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Age: above 60 years old

Exclusion Criteria:

  • Visual impairment
  • Educational inability to perform training
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00146263

Contacts
Contact: Tzvi Dwolatzky, MD 972-8-6401416 tzvidov@bgu.ac.il
Contact: Yaacov Grinshpun, MD 972-8-6401520 yaacovg@bgu.ac.il

Locations
Israel
Beersheva Mental Health Center Recruiting
Beersheva, Israel
Contact: Tzvi Dwolatzky, MD    972-8-6401416    tzvidov@bgu.ac.il   
Principal Investigator: Tzvi Dwolatzky, MD         
Sponsors and Collaborators
Beersheva Mental Health Center
Investigators
Principal Investigator: Tzvi Dwolatzky, MD Ben-Gurion University of the Negev
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00146263     History of Changes
Other Study ID Numbers: BMHC-4018CTIL
Study First Received: September 4, 2005
Last Updated: September 5, 2010
Health Authority: Israel: Israeli Health Ministry Pharmaceutical Administration

Keywords provided by Beersheva Mental Health Center:
mild cognitive impairment
dementia
Alzheimer's Disease
cognitive training

Additional relevant MeSH terms:
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on April 15, 2014