Effects of Spinal Cord Injury on Female Sexual Response

This study is currently recruiting participants.

Verified by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), October 2006

First Received: September 1, 2005 Last Updated: October 13, 2006 History of Changes

Sponsored by:	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Information provided by:	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
ClinicalTrials.gov Identifier:	NCT00142714

Purpose

The long term aims of this project are to 1) Understand the effect of varying degrees and levels of SCI and dysfunction(SCI/D)on females sexual response:

2) Identify the specific neuronal pathways involved in female sexual responses; and 3) Develop and evaluate new assessment and treatment methods for neurogenic sexual dysfunction in women.

Condition	Intervention
Female Sexual Dysfunction Multiple Sclerosis Spinal Cord Injury	Procedure: Sympathetic manipulation on sexual arousal in women

Study Type:	Interventional
Study Design:	Educational/Counseling/Training, Randomized, Open Label, Historical Control, Single Group Assignment
Official Title:	Effects of SCI on Female Sexual Response

Resource links provided by NLM:

MedlinePlus related topics: Multiple Sclerosis Spinal Cord Injuries

U.S. FDA Resources

Further study details as provided by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD):

Primary Outcome Measures:

Our central hypothesis are:
1) In females the SNS regulates psychogenic genital vasocongestion 2) In females the orgasmic reflex requires the presence of an intact sacral spinal cord, 3) In females a pattern generator is responsible for the orgasmic reflex.

Estimated Enrollment:	70
Study Start Date:	August 2003
Estimated Study Completion Date:	June 2005

Eligibility

Ages Eligible for Study:	18 Years to 55 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

MS or SCI
Normal menstrual periods
Normal hand function
Have ability to feel sensation from lower abdomen to upper thigh region.

Exclusion Criteria:

Pregnant
Menopausal

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00142714

Contacts

Contact: Paula Spath

1-866-706-5544

pspath@uab.edu

Locations

United States, Alabama
The University of Alabama at Birmingham	Recruiting
Birmingham, Alabama, United States, 35233
Contact: Paula Spath 205-934-2088 pspath@uab.edu
Principal Investigator: Marca Sipski, MD

Sponsors and Collaborators

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Investigators

Principal Investigator:

Marca Sipski, MD

The University of Alabama at Birmingham

More Information

No publications provided

Study ID Numbers:	5R01HD030149-09
Study First Received:	September 1, 2005
Last Updated:	October 13, 2006
ClinicalTrials.gov Identifier:	NCT00142714 History of Changes
Health Authority:	United States: Federal Government

Keywords provided by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD):

sexual response
sexual dysfunction in females
spinal cord injury

Study placed in the following topic categories:

Spinal Cord Injuries
Autoimmune Diseases
Multiple Sclerosis
Spinal Cord Diseases
Demyelinating Diseases
Wounds and Injuries

Disorders of Environmental Origin
Central Nervous System Diseases
Demyelinating Autoimmune Diseases, CNS
Sclerosis
Trauma, Nervous System
Autoimmune Diseases of the Nervous System

Additional relevant MeSH terms:

Autoimmune Diseases
Demyelinating Diseases
Immune System Diseases
Spinal Cord Diseases
Nervous System Diseases
Wounds and Injuries
Disorders of Environmental Origin
Central Nervous System Diseases

Sclerosis
Trauma, Nervous System
Spinal Cord Injuries
Multiple Sclerosis
Pathologic Processes
Demyelinating Autoimmune Diseases, CNS
Autoimmune Diseases of the Nervous System

ClinicalTrials.gov processed this record on July 06, 2009