Text Size

Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2006 by University Hospital Muenster.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
University Hospital Muenster
ClinicalTrials.gov Identifier:
NCT00132223
First received: August 18, 2005
Last updated: April 11, 2006
Last verified: April 2006
History of Changes
  Purpose

Angiographies of the supra-aortic vessels by magnetic imaging have become common recently. So it was the purpose of this study to evaluate the imaging potential of different contrast agents.

Three contrast agents for magnetic resonance imaging are compared in angiographies of the supra-aortic arteries in a intraindividual study of 10 patients.

All applications of these contrast agents are performed with a flow of 2 ml/s. One contrast medium is applicated a second time with a reduced flow of 1 ml/s.

The angiographies of the supra-aortic vessels are evaluated by two experienced readers in a consensus reading. The signal/noise- and contrast/noise-ratio of anatomic vessel segments of the carotic and vertebral arteries are measured and compared to each other.


Condition Intervention Phase
Headache
Epilepsy
Dizziness
 Drug: Contrast agent
 Phase 4

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Single Blind
Primary Purpose: Diagnostic
Official Title: Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients With Headache and Dizziness or Epilepsy and Clinical Indication for an Angiography by Magnetic Imaging

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University Hospital Muenster:

Primary Outcome Measures:
  • intensity of vessels, muscle, air

Secondary Outcome Measures:
  • signal/noise ratio
  • contrast/nose ratio

Estimated Enrollment: 10
Study Start Date: April 2005
Estimated Study Completion Date: December 2005
  Eligibility

Ages Eligible for Study:   18 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Headache
  • Epilepsia
  • Dizziness

Exclusion Criteria:

  • Pregnancy
  • Metal implants (e.g. pacemaker)
  • Contraindication for contrast agent
  • Multiple allergies
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00132223

Contacts
Contact: Boris Buerke, MD 00492518345123 buerkeb@uni-muenster.de
Contact: Bernd Tombach, MD 00492518345123 tombach@uni-muenster.de

Locations
Germany
University of Muenster, Dept. of Clinical Radiology Recruiting
Muenster, Germany, 48129
Contact: Boris Buerke, MD     00492518345123     buerkeb@uni-muenster.de    
Contact: Bernd Tombach     00492518345123     tombach@uni-muenster.de    
Principal Investigator: Bernd Tombach, MD            
Sub-Investigator: Boris Buerke, MD            
Sponsors and Collaborators
University Hospital Muenster
Investigators
Study Chair: Bernd Tombach, MD University of Muenster, Dept. of Clinical Radiology
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00132223     History of Changes
Other Study ID Numbers: 0710/2004-IKR
Study First Received: August 18, 2005
Last Updated: April 11, 2006
Health Authority: Germany: Federal Institute for Drugs and Medical Devices

Keywords provided by University Hospital Muenster:
magnetic imaging
angiography
contrast agent
 signal/noise ratio
contrast/noise ratio
vessel

Additional relevant MeSH terms:
Dizziness
Vertigo
Epilepsy
Headache
Sensation Disorders
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
 Vestibular Diseases
Labyrinth Diseases
Ear Diseases
Otorhinolaryngologic Diseases
Brain Diseases
Central Nervous System Diseases
Pain

ClinicalTrials.gov processed this record on May 19, 2013