Effect of Lifestyle Factors and Hormone Function on Breast Density in Healthy Hispanic Women Who Are Undergoing Mammography for Breast Cancer Screening
RATIONALE: Lifestyle factors, such as physical activity, diet, and obesity, and hormone function may affect breast density. Screening tests, such as mammography, may help doctors find tumor cells early and plan better treatment for breast cancer.
PURPOSE: This clinical trial is studying the effect of lifestyle factors and hormone function on breast density in healthy Hispanic women who are undergoing mammography for breast cancer screening.
Other: physiologic testing
Other: study of socioeconomic and demographic variables
Procedure: breast imaging study
Procedure: study of high risk factors
|Study Design:||Primary Purpose: Screening|
|Official Title:||Chicago Breast Health Project, Phase II|
|Study Start Date:||August 2003|
- Correlate physical activity, diet, and obesity, as measured by body mass index and waist circumference, with percent breast density and the absolute estimate of total dense breast area in healthy Hispanic women undergoing screening mammography.
- Correlate fasting serum insulin growth factor (IGF)-1 and the molar ratio of IGF-1 to IGF binding protein-3 with breast density in participants undergoing screening mammography.
- Correlate insulin concentration and insulin resistance with breast density in participants undergoing screening mammography.
OUTLINE: This is a multicenter study.
Participants undergo blood collection and physical examination. Participants also complete breast cancer risk factor, food frequency, and physical activity questionnaires and receive breast health and physical activity education. Participants then undergo a digital screening mammogram. Participants are notified of mammogram results.
PROJECTED ACCRUAL: A total of 114 participants will be accrued for this study.
|United States, Illinois|
|Robert H. Lurie Comprehensive Cancer Center at Northwestern University|
|Chicago, Illinois, United States, 60611|
|Principal Investigator:||Susan M. Gapstur||Robert H. Lurie Cancer Center|