Primary Outcome Measures:
- Diffusion-tensor imaging differences between brain injured cases and controls without brain injury [ Time Frame: 2 years ] [ Designated as safety issue: No ]
Secondary Outcome Measures:
- Umbilical cord gas results [ Time Frame: 2 years ] [ Designated as safety issue: No ]
- Placental pathology [ Time Frame: 2 years ] [ Designated as safety issue: No ]
- Electronic fetal monitoring [ Time Frame: 2 years ] [ Designated as safety issue: No ]
- Nucleated red blood cells [ Time Frame: 2 years ] [ Designated as safety issue: No ]
Procedure: Diffusion-tensor imaging
Obtain a Diffusion tensor MRI of brain.
Other Name: No other names applicable.
Maternal and neonatal data will be collected as well as the umbilical arterial gas results and the electronic fetal heart rate tracing of the labor. Infants will have a head ultrasound at 24-72 hours, 10-14 days, and at 4-6 weeks to look for cerebral white matter injury, as standard of care. All infants with a birth weight < 1500 grams will be offered DTI, and infants > 1500 grams with white matter injury diagnosed by ultrasound will be imaged as well as the subsequent delivery born within 7 days of that gestational age without brain injury. All infants will have the DTI brain scan at 12-18 months of age corrected for the degree of prematurity, and will also have a formal neurological assessment at that time.