Effects of Neighborhood SES on Coronary Heart Disease Burden in Communities - Ancillary to ARIC

This study has been completed.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Kathryn Rose, University of North Carolina, Chapel Hill
ClinicalTrials.gov Identifier:
NCT00106951
First received: April 1, 2005
Last updated: January 29, 2012
Last verified: January 2012
  Purpose

To investigate the role of racial and socioeconomic disparities in coronary heart disease (CHD) mortality in the United States.


Condition
Cardiovascular Diseases
Coronary Disease
Heart Diseases

Study Type: Observational
Study Design: Time Perspective: Retrospective
Official Title: Effects of Neighborhood SES on Coronary Heart Disease Burden in Communities - Ancillary to ARIC

Resource links provided by NLM:


Further study details as provided by University of North Carolina, Chapel Hill:

Enrollment: 12000
Study Start Date: April 2005
Study Completion Date: March 2009
Primary Completion Date: March 2009 (Final data collection date for primary outcome measure)
Detailed Description:

BACKGROUND:

Despite strong decreases in coronary heart disease (CHD) mortality over past decades, there is evidence that racial and socioeconomic disparities in CHD mortality are increasing. CHD surveillance efforts that examine trends within these population subgroups are an important first step in quantifying and reducing disparities. The Atherosclerosis Risk in Communities (ARIC) Study has monitored rates and trends in validated hospitalized myocardial infarction and fatal CHD among black and white adults aged 35 to 74 years in four U.S. communities since 1989.

DESIGN NARRATIVE:

The study will expand the scope of ARIC surveillance by examining variations in the rates and temporal trends in CHD by socioeconomic status (SES), measured at the level of census tract. For CHD events already included in ARIC surveillance (1992-2002), addresses will be obtained from medical records and death certificates and geocoded so that they can be matched with identifiers for census based geographical areas. The ARIC study will contribute yearly updates of abstracted CHD events and addresses for subsequent years (2003-2005). Each event will be linked with census tract level SES indicators available from the 1990 and 2000 censuses. This novel effort will permit an examination of disparities by SES in rates and trends in fatal CHD, hospitalized myocardial infarction, case fatality, use of invasive cardiac procedures and prescription of efficacious medication at time of hospital discharge. In addition, the extent to which racial disparities in CHD and associated treatments are explained by SES will also be explored.

  Eligibility

Ages Eligible for Study:   35 Years to 74 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Community surveillance of adults in four communities in the US

Criteria

hospitalized and fatal coronary heart disease cases eligibility: within 4 defined geographic areas and ages 35 to 74 years of age

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00106951

Sponsors and Collaborators
University of North Carolina, Chapel Hill
Investigators
Principal Investigator: Kathryn M Rose, PhD UNC (Adjunct)
  More Information

Publications:
Responsible Party: Kathryn Rose, Adjunct Associate Professor, University of North Carolina, Chapel Hill
ClinicalTrials.gov Identifier: NCT00106951     History of Changes
Other Study ID Numbers: 1292, R01HL080287
Study First Received: April 1, 2005
Last Updated: January 29, 2012
Health Authority: United States: Federal Government

Keywords provided by University of North Carolina, Chapel Hill:
Surveillance
coronary heart disease
neighborhood SES

Additional relevant MeSH terms:
Cardiovascular Diseases
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases

ClinicalTrials.gov processed this record on August 27, 2014