2 Doses of an Approved Drug Being Studied for a New Indication for the Prevention of Postoperative Nausea and Vomiting (0869-091)(COMPLETED)
The purpose of this study is to assess the safety and efficacy of 2 doses of an approved drug for a new indication in the prevention of postoperative nausea and vomiting in patients receiving general anesthesia for open abdominal surgery requiring overnight hospital stay.
Postoperative Nausea and Vomiting
Drug: MK0869, aprepitant
Drug: Comparator: ondansetron IV
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Prevention
|Official Title:||A Randomized, Double-Blind, Active Comparator-Controlled, Parallel-Group Study, Conducted Under In-House Blinding Conditions, to Examine the Safety, Tolerability, and Efficacy of 2 Doses of Aprepitant for the Prevention of Postoperative Nausea and Vomiting|
- Prevention of PONV in the 24 hours following end of surgery; Tolerability [ Time Frame: 24 hours ]
|Study Start Date:||May 2004|
|Primary Completion Date:||April 2005 (Final data collection date for primary outcome measure)|
The duration of treatment is 4 weeks.