Cognitive Behavioral Therapy for the Treatment of Seasonal Affective Disorder (SAD)

This study has been completed.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Kelly Rohan, Henry M. Jackson Foundation for the Advancement of Military Medicine
ClinicalTrials.gov Identifier:
NCT00076245
First received: January 16, 2004
Last updated: June 24, 2014
Last verified: June 2014
  Purpose

This study will assess the effectiveness of cognitive behavioral therapy (CBT) in treating seasonal affective disorder (SAD), commonly called the "winter blues."


Condition Intervention Phase
Seasonal Affective Disorder
Depression
Behavioral: Light Therapy
Behavioral: Cognitive behavioral therapy (CBT)
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Treatment
Official Title: Cognitive Behavioral Approaches to Seasonal Depression

Resource links provided by NLM:


Further study details as provided by Henry M. Jackson Foundation for the Advancement of Military Medicine:

Primary Outcome Measures:
  • Scores on the Structured Interview Guide for the Hamilton Depression Rating Scale—Seasonal Affective Disorder Version [ Time Frame: Post-treatment ] [ Designated as safety issue: No ]
    The Structured Interview Guide for the Hamilton Depression Rating Scale—Seasonal Affective Disorder Version (SIGH-SAD) measures depressive symptoms on a continuous scale. Higher scores indicate worse outcome. Range of scores is 0 to 73. Generally, a score of 20 or higher is the cutoff for clinical depression.

  • Remission Status on Structured Interview Guide for the Hamilton Depression Rating Scale—Seasonal Affective Disorder Version (SIGH-SAD) [ Time Frame: Post-treatment ] [ Designated as safety issue: No ]
    Dichotomous Remission Status (remitted or not) at post-treatment


Enrollment: 61
Study Start Date: November 2002
Study Completion Date: November 2005
Primary Completion Date: February 2004 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1 Light therapy Behavioral: Light Therapy
Light therapy will involve exposure to bright light twice a day.
Experimental: 2 Cognitive behavioral therapy Behavioral: Cognitive behavioral therapy (CBT)
CBT attempts to change maladaptive thoughts and beliefs, and will be conducted twice a week.
Experimental: 3 Light therapy plus cognitive behavioral therapy Behavioral: Light Therapy
Light therapy will involve exposure to bright light twice a day.
Behavioral: Cognitive behavioral therapy (CBT)
CBT attempts to change maladaptive thoughts and beliefs, and will be conducted twice a week.
No Intervention: 4 Control

Detailed Description:

SAD is a condition in which people experience depression as a result of seasonal variations in sunlight. Although light therapy is a common treatment for SAD, a large proportion of people with SAD are resistant to this treatment. CBT is effective for nonseasonal depressive disorders, but its use for SAD has not been thoroughly explored. This study will determine whether CBT, alone and combined with light therapy, is as effective as light therapy alone in reducing SAD symptoms.

Participants in this study will be randomly assigned to light therapy, CBT, a combination of light therapy and CBT, or a control group (no therapy) for 6 weeks. CBT will be conducted twice a week; light therapy will be conducted twice a day. Assessments will be made before, during, and after the study treatment. Depression scales, questionnaires, and behavioral tasks will be used to assess the depressive symptoms of participants. A 6-month and 1-year follow-up visit will also be conducted. During the follow-up visits, participants will be interviewed and will complete a questionnaire and a survey.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Diagnosis of seasonal affective disorder (SAD)
  • Willing and able to participate in the study procedures

Exclusion Criteria:

  • Major psychological diagnoses other than SAD
  • Current psychological or psychiatric treatment
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00076245

Locations
United States, Maryland
Uniformed Services University of the Health Sciences (USUHS)
Bethesda, Maryland, United States, 20814-4799
Sponsors and Collaborators
Henry M. Jackson Foundation for the Advancement of Military Medicine
Investigators
Principal Investigator: Kelly J. Rohan, PhD Uniformed Services University of the Health Sciences (USUHS)
  More Information

Additional Information:
No publications provided

Responsible Party: Kelly Rohan, Principal Investigator, Henry M. Jackson Foundation for the Advancement of Military Medicine
ClinicalTrials.gov Identifier: NCT00076245     History of Changes
Other Study ID Numbers: R03 MH65946, R03MH065946, DSIR AT-AS
Study First Received: January 16, 2004
Results First Received: February 24, 2014
Last Updated: June 24, 2014
Health Authority: United States: Federal Government

Keywords provided by Henry M. Jackson Foundation for the Advancement of Military Medicine:
Phototherapy

Additional relevant MeSH terms:
Depression
Depressive Disorder
Disease
Mood Disorders
Seasonal Affective Disorder
Behavioral Symptoms
Mental Disorders
Pathologic Processes

ClinicalTrials.gov processed this record on October 16, 2014