Genetic Registry for Rheumatoid Arthritis (NARAC)
Many genes are thought to contribute to rheumatoid arthritis (RA). This study will attempt to identify genes that may contribute to RA.
|Study Design:||Observational Model: Family-Based
Time Perspective: Cross-Sectional
|Official Title:||Genetics of Rheumatoid Arthritis Registry|
- Genetic Association with risk for rheumatoid arthritis [ Time Frame: 3 years ] [ Designated as safety issue: No ]The project aims to identify one or more risk alleles for rheumatoid arthritis using association methods in trio families, combeined with data from singleton cases and multiplex families
Biospecimen Retention: Samples With DNA
DNA, plasma, serum and cells
|Study Start Date:||October 2002|
|Estimated Study Completion Date:||July 2015|
|Estimated Primary Completion Date:||July 2013 (Final data collection date for primary outcome measure)|
The identification of genes for complex disorders such as RA requires large numbers of genetically informative families. This study enrolls people diagnosed with with RA and their families.
This study will enroll 1000 RA patients and their parents. Participants with RA will be evaluated at his or her doctor's office or other location convenient for the participant. Participants will have a brief phone interview with a study coordinator and a blood sample will be obtained. Disease evaluation will be done at one visit and will include confirmation of diagnosis, a 28 joint count, joint alignment and mobility score (JAMS) and administration of a health assessment questionnaire.
|United States, New York|
|Feinstein Institute for Medical Research|
|Manhasset, New York, United States, 11030|
|Principal Investigator:||Peter K. Gregersen, MD||North Shore University Hospital|