Therapy for Reading Problems in Adults After Brain Injury
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Purpose
Adults who sustain brain damage due to stroke, head injury, or traumatic surgery may develop difficulty reading. This study examines the effectiveness of behavior-based programs to improve reading ability in these individuals.
| Condition | Intervention |
|---|---|
|
Dyslexia, Acquired Brain Injuries Cerebrovascular Accident |
Behavioral: Cognitive Therapy to Improve Reading |
| Study Type: | Interventional |
| Study Design: | Allocation: Non-Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Treatment |
| Official Title: | Cognitively-Based Treatments of Acquired Dyslexias |
- Improved accuracy and/or speed of reading individual words aloud.
- Improved accuracy and/or speed of reading text aloud.
| Estimated Enrollment: | 58 |
| Study Start Date: | August 2002 |
| Estimated Study Completion Date: | July 2007 |
Acquired disorders of reading (acquired dyslexia) are common in patients with aphasia subsequent to left hemisphere stroke. Even when language functions recover sufficiently to enable the patient to return to work, continuing dyslexia often interferes significantly with job performance. This study will evaluate cognitive therapies for the treatment of acquired dyslexia.
Each therapy is based upon a cognitive neuropsychological model of reading; the therapies target specific types of reading deficit and stem from the question of re-learning versus re-organization of function. The therapies focus on dyslexic disorders stemming from the following underlying deficits: 1) impaired access to the orthographic word form from the visual modality (pure alexia); 2) impaired orthographic/phonologic connections (phonologic/deep dyslexia); and 3) decreased ability to hold phonologic codes in memory (phonologic text alexia).
Participants in this study will undergo a comprehensive and detailed battery of reading and reading-related tests to determine the underlying impairment causing the reading deficit. Based upon the results of these tests, the patient's dyslexic disorder will be characterized and, if appropriate, the patient will be assigned to one of the treatment programs devised specifically for that type of deficit. Treatment programs are evaluated for efficacy by comparing the accuracy and speed of reading pre- and post-treatment.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria
- Reading deficit subsequent to stroke, traumatic brain injury, brain surgery, or other brain damage
- Ability to attend 2-3 sessions per week for several months at Georgetown University in Washington, DC
Exclusion Criteria
- History of developmental dyslexia or learning disabilities
- Best corrected vision less than 20/40
- Less than 10 years of formal education
- Significant memory or comprehension problems
Contacts and Locations| Contact: Sarah F. Snider, MA, SLP | sfs24@georgetown.edu | |
| Contact: Nora L. Watson, BS | nlw9@georgetown.edu |
| United States, District of Columbia | |
| Georgetown University Medical Center | Recruiting |
| Washington, District of Columbia, United States, 20057 | |
| Principal Investigator: | Rhonda B. Friedman, Ph.D. | Georgetown University Medical School |
More Information
Additional Information:
Publications:
| ClinicalTrials.gov Identifier: | NCT00064805 History of Changes |
| Other Study ID Numbers: | R01HD36019 |
| Study First Received: | July 14, 2003 |
| Last Updated: | September 11, 2008 |
| Health Authority: | United States: Federal Government |
Keywords provided by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD):
|
Cognitive therapy Aphasia therapy Alexia Acquired dyslexia Phonological deficits |
Orthographic deficits Brain disorders Brain injury Stroke |
Additional relevant MeSH terms:
|
Communication Disorders Dyslexia, Acquired Cerebral Infarction Stroke Brain Injuries Dyslexia Language Disorders Neurobehavioral Manifestations Neurologic Manifestations Nervous System Diseases Learning Disorders Signs and Symptoms Delirium, Dementia, Amnestic, Cognitive Disorders |
Mental Disorders Mental Disorders Diagnosed in Childhood Brain Infarction Brain Ischemia Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Vascular Diseases Cardiovascular Diseases Craniocerebral Trauma Trauma, Nervous System Wounds and Injuries |
ClinicalTrials.gov processed this record on May 16, 2013