A Trial of Tap Water Treatment in the Elderly
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Purpose
This study is being conducted in Sonoma County, California.
Gastrointestinal illness and diarrhea are recognized as a significant cause of morbidity and mortality in the elderly. One study showed that 51% of deaths caused by diarrhea over a 9-year period occurred in individuals over the age of 74 years. Although many infectious diseases are more problematic in the elderly because of a decline in immune function and a higher incidence of pre-existing malnutrition and dehydration, it is still not known what the principal modes of transmission are and which infectious agents are responsible.
The principal objective of this study is to evaluate the ability of in-home treatment of tapwater to reduce gastrointestinal illness in non-institutionalized elderly individuals. The trial will test household-level treatment of drinking water by joint use of ultraviolet light and filtration devices. A secondary objective is an estimate of the incidence of specific bacterial, viral, and protozoan agents in stool specimens collected from elderly individuals with gastrointestinal symptoms that might be related to water consumption.
| Condition | Intervention |
|---|---|
|
Diarrhea Gastrointestinal Diseases |
Device: home drinking water treatment device |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Crossover Assignment Masking: Double-Blind Primary Purpose: Prevention |
| Official Title: | A Randomized Trial of Tap Water Treatment in the Elderly |
| Estimated Enrollment: | 810 |
| Study Start Date: | January 2000 |
| Study Completion Date: | November 2006 |
| Primary Completion Date: | November 2006 (Final data collection date for primary outcome measure) |
Show Detailed Description Eligibility| Ages Eligible for Study: | 55 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Inclusion Criteria
- 55 years or older
- primary source of drinking water used at home is supplied by Sonoma County Water Agency without use of home filtration device or bottled water
- all individuals living in the home must sign informed consent and agree to have the water treatment device installed
- no known immunocompromising conditions (including HIV/AIDS, active cancer, or transplant recipients).
Exclusion criteria:
- persons with immunocompromising condition (including HIV/AIDS, active cancer, or transplant recipients)
- employees and family members of the Sonoma County Water Agency or a Sonoma County Water District
Contacts and Locations| United States, California | |
| University of California Berkeley | |
| Berkeley, California, United States, 94720 | |
| Principal Investigator: | John M. Colford, M.D., Ph.D. | School of Public Health, University of California at Berkeley |
More Information
Publications:
| ClinicalTrials.gov Identifier: | NCT00058942 History of Changes |
| Other Study ID Numbers: | AG0002, 5R01AG016634-03 |
| Study First Received: | April 15, 2003 |
| Last Updated: | December 9, 2009 |
| Health Authority: | United States: Federal Government |
Keywords provided by National Institute on Aging (NIA):
|
Drinking Water |
Additional relevant MeSH terms:
|
Diarrhea Gastrointestinal Diseases Digestive System Diseases Signs and Symptoms, Digestive Signs and Symptoms |
ClinicalTrials.gov processed this record on May 19, 2013