Marijuana for Cancer Pain
To find out if it is safe and effective to use smoked marijuana in combination with opioids to treat cancer pain. The study will evaluate whether smoked marijuana, when used with opioids, will have an effect on pain relief, and to see if marijuana reduces the side effects of opioids, which include nausea and/or vomiting.
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Marijuana in Combination With Opioids for Cancer Pain: A Pilot Study|
- Change in level of cancer pain as recorded on a 100mm Visual Analog Scale.
- Change in level of experimentally induced pain on a 100mm Visual Analog Scale.
- Change in nausea and emesis in participants exhibiting these symptoms.
- Change in disposition kinetics of opioid analgesics.
|Study Start Date:||September 2002|
|Study Completion Date:||October 2004|
To take part in this study, you must have ongoing cancer pain which is currently being treated with opioids. If you meet all the eligibility criteria you will be admitted to the General Clinical Research Center at San Francisco General Hospital for 9 days. The treatment consists of smoking one marijuana cigarette 3 times a day.
|United States, California|
|University of California, San Francisco|
|San Francisco, California, United States, 94110|
|Principal Investigator:||Donald I Abrams, M.D.||UCSF Community Consortium|