Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease

This study has been completed.
Sponsor:
Information provided by:
National Center for Complementary and Alternative Medicine (NCCAM)
ClinicalTrials.gov Identifier:
NCT00034112
First received: April 22, 2002
Last updated: August 17, 2006
Last verified: July 2006
  Purpose

The purpose of this study is to determine if osteopathic manipulative treatment (OMT) is effective for persons with emphysema as a component of their chronic obstructive pulmonary disease.


Condition Intervention Phase
Emphysema
Procedure: osteopathic manipulative treatment
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Primary Purpose: Treatment
Official Title: Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease

Resource links provided by NLM:


Further study details as provided by National Center for Complementary and Alternative Medicine (NCCAM):

Study Start Date: April 2001
Estimated Study Completion Date: March 2002
Detailed Description:

OMT sessions are designed to improve chest wall compliance and diaphragmatic function which produce an immediate positive change in pulmonary function parameters and chest wall mobility. This research project will be a significant step in expanding the understanding of the role of OMT in the treatment of chronic lung disease. It is expected to yield evidence that OMT is an important adjunctive modality that improves pulmonary function, increases exercise tolerance, relieves dyspnea, and improves quality of life in those with COPD, and that would have widespread clinical application plus significant economic benefits.

Participants in this study will be randomly assigned to receive either OMT or sham treatments once a week for 13 weeks. Outcome measures will be obtained at baseline; immediately following the first treatment; at 4, 8, and 12 weeks after initiation of treatment; and 4 weeks after termination of the treatment. Outcome variables include pulmonary function tests; quality-of-life questionnaires (including emotional functioning, fatigue, and dyspnea); and measurements of exercise tolerance and chest wall mobility.

  Eligibility

Accepts Healthy Volunteers:   No
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00034112

Locations
United States, Missouri
Kirksville College of Osteopathic Medicine
Kirksville, Missouri, United States, 63501
Sponsors and Collaborators
Investigators
Principal Investigator: Donald R. Noll Kirksville College of Osteopathic Medicine
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00034112     History of Changes
Other Study ID Numbers: R21 AT000207-01A1
Study First Received: April 22, 2002
Last Updated: August 17, 2006
Health Authority: United States: Federal Government

Keywords provided by National Center for Complementary and Alternative Medicine (NCCAM):
chronic obstructive pulmonary disease
combination therapy,
emphysema
exercise
human therapy evaluation
rehabilitation
respiratory disease /disorder therapy
respiratory function
biomechanics
body movement
diaphragm
dyspnea
muscle tension
musculoskeletal system
outcomes research
quality of life
somatic reflex

Additional relevant MeSH terms:
Emphysema
Pulmonary Emphysema
Lung Diseases
Pulmonary Disease, Chronic Obstructive
Lung Diseases, Obstructive
Pathologic Processes
Respiratory Tract Diseases

ClinicalTrials.gov processed this record on August 21, 2014