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| Sponsored by: |
Department of Veterans Affairs |
| Information provided by: | Department of Veterans Affairs |
| ClinicalTrials.gov Identifier: | NCT00018785 |
Purpose
Diabetes and end-stage kidney, liver and heart disease are prominent health issues among veteran patients. Successful solid organ transplantation in the absence of chronic immunosuppressive therapy (specific acquired immunological tolerance) is a desirable therapeutic option. This project extends recent observations supporting the use of concommitant donor bone marrow cell infusion as a means of modulating the immune response in kidney transplantation, thereby allowing a substantial decrease or withdrawal of potentially toxic immunosuppressive drugs.
| Condition | Intervention |
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Kidney Disease |
Procedure: donor bone marrow infusion |
| MedlinePlus related topics: | Kidney Transplantation |
| Study Type: | Interventional |
| Study Design: | Prevention, Open Label, Active Control, Parallel Assignment, Efficacy Study |
| Official Title: | Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants |
Eligibility
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Living related donor kidney transplant recipients and the living related donors.
Contacts and Locations| United States, Florida | |||||
| VAMC Miami | |||||
| Miami, Florida, United States, 33125 | |||||
| Investigator: | Camillo Ricordi, M.D. | |
| Investigator: | Andreas Tzakis, M.D. | |
| Investigator: | Violet Esquenazi, Ph.D. | |
| Investigator: | Keith Zucker, Ph.D. |
More Information
| Study ID Numbers: | IMMU-035-98S |
| First Received: | July 3, 2001 |
| Last Updated: | June 23, 2005 |
| ClinicalTrials.gov Identifier: | NCT00018785 |
| Health Authority: | United States: Federal Government |
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