Biological Aspects of Depression and Antidepressant Drugs

This study has been completed.
Sponsor:
Information provided by:
Department of Veterans Affairs
ClinicalTrials.gov Identifier:
NCT00018733
First received: July 3, 2001
Last updated: January 20, 2009
Last verified: December 2004
  Purpose

This study will be measuring changes in depressive symptoms over a 7 week time period. Double-blind placebo controlled trial using the pharmacologic agents Paroxetine or Desipramine.


Condition Intervention
Depression
Drug: paroxetine
Drug: Desipramine

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Pharmacodynamics Study
Masking: Double-Blind
Primary Purpose: Treatment
Official Title: Biological Aspects of Depression and Antidepressant Drugs

Resource links provided by NLM:


Further study details as provided by Department of Veterans Affairs:

Study Start Date: September 1996
Estimated Study Completion Date: December 2001
  Eligibility

Ages Eligible for Study:   21 Years to 69 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria
  • Diagnosis of major depressive disorder Ham-D Score > 18
  • English speaking with ability to read and sign an informed consent
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00018733

Locations
United States, Texas
South Texas Veterans Health Care System
San Antonio, Texas, United States, 78229
Sponsors and Collaborators
Investigators
Investigator: Steve Brannan, M.D.
Investigator: Cheryl Gonzalez, M.D.
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00018733     History of Changes
Other Study ID Numbers: MHBS-031-99F
Study First Received: July 3, 2001
Last Updated: January 20, 2009
Health Authority: United States: Federal Government

Keywords provided by Department of Veterans Affairs:
Depression

Additional relevant MeSH terms:
Depression
Depressive Disorder
Behavioral Symptoms
Mood Disorders
Mental Disorders
Antidepressive Agents
Psychotropic Drugs
Central Nervous System Agents
Therapeutic Uses
Pharmacologic Actions

ClinicalTrials.gov processed this record on October 16, 2014