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Integrated Intervention for Substance Abusers With Depressive Disorders
This study is ongoing, but not recruiting participants.
First Received: July 3, 2001   Last Updated: January 16, 2009   History of Changes
Sponsor: Department of Veterans Affairs
Information provided by: Department of Veterans Affairs
ClinicalTrials.gov Identifier: NCT00018655
  Purpose

This study is a randomized clinical trial comparing outcomes of Integrated Cognitive Behavioral Treatment plus standard medications for veterans with both substance use disorders, depressive disorders versus the most commonly administered form of therapy for substance use disorders and depression, Twelve Step Facilitation (AA/NA model) group treatment plus medications.


Condition Intervention Phase
Substance-Related Disorders
Depressive Disorder
Behavioral: Twelve Step Facilitation
Behavioral: Integrated Cognitive Behavioral Treatment
Phase II

Study Type: Interventional
Study Design: Treatment, Randomized, Single Blind (Outcomes Assessor), Uncontrolled, Factorial Assignment, Safety Study
Official Title: Integrated Intervention for Substance Abusers With Depressive Disorders

Resource links provided by NLM:


Further study details as provided by Department of Veterans Affairs:

Primary Outcome Measures:
  • Hamilton Depression Scale, Timeline Follow-back (substance measure) [ Time Frame: 18 months ] [ Designated as safety issue: No ]

Enrollment: 276
Study Start Date: April 2000
Estimated Study Completion Date: September 2012
Estimated Primary Completion Date: September 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
1: Experimental
Twelve Step Facilitation
Behavioral: Twelve Step Facilitation
Twelve Step Facilitation Therapy involves focusing on topics from 12-Step programs which support sobriety goals and personal growth.
2: Experimental
Integrated Cognitive Behavioral Treatment
Behavioral: Integrated Cognitive Behavioral Treatment
Integrated Cognitive Behavioral Treatment involves focusing on thoughts, activities, and interactions with people related to depressive symptoms and/or substance use.

Detailed Description:

This study is a randomized clinical trial comparing outcomes of Integrated Cognitive Behavioral Treatment plus standard medications for veterans with both substance use disorders, depressive disorders versus the most commonly administered form of therapy for substance use disorders and depression, Twelve Step Facilitation (AA/NA model) group treatment plus medications. Follow-up assessments were conducted at quarterly intervals for one year following treatment.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

Veterans age 18 and older with alcohol, cannabinol, and/or stimulant dependence and independent mood disorders will be included.

Exclusion Criteria:

Psychotic disorders

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00018655

Locations
United States, California
VA San Diego Healthcare System, San Diego
San Diego, California, United States, 92161
Sponsors and Collaborators
Investigators
Principal Investigator: Sandra Brown, PhD VA San Diego Healthcare System, San Diego
  More Information

Publications:
Responsible Party: Department of Veterans Affairs ( Brown, Sandra - Principal Investigator )
Study ID Numbers: MHBS-041-99S
Study First Received: July 3, 2001
Last Updated: January 16, 2009
ClinicalTrials.gov Identifier: NCT00018655     History of Changes
Health Authority: United States: Federal Government

Keywords provided by Department of Veterans Affairs:
Mood Disorders
Substance-Related Disorders

Additional relevant MeSH terms:
Pathologic Processes
Disease
Depression
Mental Disorders
Mood Disorders
Substance-Related Disorders
Disorders of Environmental Origin
Depressive Disorder
Behavioral Symptoms

ClinicalTrials.gov processed this record on November 30, 2009