Protection Against Benzene Toxicity - Full Text View

Protection Against Benzene Toxicity

This study has been completed.

Sponsored by:	National Institute of Environmental Health Sciences (NIEHS)
Information provided by:	National Institute of Environmental Health Sciences (NIEHS)
ClinicalTrials.gov Identifier:	NCT00011453

Purpose

We are investigating the role of an enzyme (NQO1) in protection against the bone marrow toxicity of the occupational and environmental toxicant benzene. All of the proposed studies involve use of human bone marrow cells in-vitro to define mechanisms of NQO1-mediated protection. Cells are obtained from healthy volunteers and protocols have undergone IRB review and approval.

Condition

Leukemia
Aplastic Anemia

MedlinePlus related topics:

Anemia Leukemia, Adult Acute Leukemia, Adult Chronic

U.S. FDA Resources

Study Type:	Observational
Study Design:	Screening, Convenience Sample, Prospective Study

Official Title:	NQO1 in Protection Against Benzene Toxicity

Further study details as provided by National Institute of Environmental Health Sciences (NIEHS):

Study Start Date:	July 1998
Estimated Study Completion Date:	June 2001

Eligibility

Ages Eligible for Study:	21 Years to 65 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Healthy adult volunteers with blood counts in normal ranges and without evidence of hepatitis or HIV infection.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00011453

Locations


United States, Colorado
	University of Colorado Health Sciences Center
	Denver, Colorado, United States, 80262

Sponsors and Collaborators

National Institute of Environmental Health Sciences (NIEHS)

More Information

Study ID Numbers:	9554-CP-001
First Received:	February 21, 2001
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00011453
Health Authority:	United States: Federal Government