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| Sponsor: | Department of Veterans Affairs |
|---|---|
| Collaborators: |
Department of Defense Centers for Disease Control and Prevention Department of Health and Human Services ALS Association |
| Information provided by: | Department of Veterans Affairs |
| ClinicalTrials.gov Identifier: | NCT00007722 |
Purpose
Recently, concern has arisen regarding a possible elevated occurrence of ALS among veterans who served in the Persian Gulf during Operations Desert Shield (August 2, 1990 - January 15, 1991), Desert Storm (January 16, 1991 - February 28, 1991) and Clean-up (March 1, 1991 - July 31, 1991). This study involves an epidemiologic investigation into the occurrence of ALS among veterans of the Gulf War. This study will further define the epidemiology of this neurological disease among younger individuals while determining whether there is a higher than expected occurrence. It will also ascertain the etiologic importance of deployment to the Persian Gulf and exposure to specific environmental factors in that geographic area. VA is leading this joint federal government epidemiologic study that also involves DoD, HHS, CDC, and academic centers of excellence in neurology, with advice from the ALS Association.
| Condition |
|---|
|
Amyotrophic Lateral Sclerosis |
| Study Type: | Observational |
| Study Design: | Case-Only, Prospective |
| Official Title: | CSP #500 - An Epidemiological Investigation Into the Occurrence of Amyotrophic Lateral Sclerosis (ALS) Among Gulf War Veterans |
DNA samples of blood or mouthwash were collected in veterans' homes by nurses.
| Enrollment: | 135 |
| Study Start Date: | July 2000 |
| Study Completion Date: | March 2003 |
| Primary Completion Date: | March 2003 (Final data collection date for primary outcome measure) |
Show Detailed Description Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Living and deceased veterans with an ALS diagnosis who served in the military between 8/2/1990 and 7/31/1991.
Inclusion Criteria:
Veterans who served in the Persian Gulf during Operations Desert Shield (August 2, 1990 - January 15, 1991), Desert Storm (January 16, 1991 - February 28, 1991) and Clean-up (March 1, 1991 - July 31, 1991)
Exclusion Criteria:
Contacts and Locations| United States, North Carolina | |
| VA Medical Center | |
| Durham, North Carolina, United States, 27705 | |
| Study Chair: | Eugene Z. Oddone, MD MHSc | Department of Veterans Affairs |
More Information
| Responsible Party: | Department of Veterans Affairs ( Oddone, Eugene - Study Chair ) |
| Study ID Numbers: | 500 |
| Study First Received: | December 29, 2000 |
| Last Updated: | October 7, 2009 |
| ClinicalTrials.gov Identifier: | NCT00007722 History of Changes |
| Health Authority: | United States: Federal Government |
|
ALS amyotrophic lateral sclerosis Gulf War Veterans |
|
Pathologic Processes Neuromuscular Diseases Spinal Cord Diseases Amyotrophic Lateral Sclerosis Nervous System Diseases |
Central Nervous System Diseases Sclerosis Neurodegenerative Diseases Motor Neuron Disease |
