Angiotensin-Converting Enzyme Gene Polymorphism and the Risk of Chronic Allograft Nephropathy

This study has been completed.

First Received: October 4, 2000 Last Updated: June 23, 2005 History of Changes

Sponsor:	National Center for Research Resources (NCRR)
Information provided by:	National Center for Research Resources (NCRR)
ClinicalTrials.gov Identifier:	NCT00006328

Purpose

This study is intended to help doctors learn about the relationships between specific genetic makeup (gene markers) and the development of chronic rejection. This study is being done to see if there is a relationship between genetic patterns and the development of Chronic Allograft Nephropathy (CAN). Medical scientists also hope to learn more about how genetic differences between people determine their response to a drug or a disease by storing a small blood sample in a special "bank". This sample may be tested at some point in the future in an attempt to better understand the factors that may influence rejection, transplantation outcomes and transplant success rates.

Condition
Kidney Disease

Study Type:	Observational
Study Design:	Natural History, Retrospective Study

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

All subjects must be recipients of a renal allograft.
Study subjects must have evidence of biopsy-proven Chronic Allograft Nephropathy (CAN).
Control subjects must not have evidence of CAN.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00006328

Locations

United States, Michigan
Univ. of Michigan Health System
Ann Arbor, Michigan, United States, 48109-0391,

Sponsors and Collaborators

National Center for Research Resources (NCRR)

More Information

No publications provided

Study ID Numbers:	NCRR-M01RR00042-1678, M01RR00042
Study First Received:	October 4, 2000
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00006328 History of Changes
Health Authority:	United States: Federal Government

Keywords provided by National Center for Research Resources (NCRR):

Chronic Allograft Nephropathy (CAN)
Transplantation immunology
Genetics
Graft Rejection

Additional relevant MeSH terms:

Urologic Diseases
Kidney Diseases

ClinicalTrials.gov processed this record on November 25, 2009