Study of the Regulation of Parathyroid Hormone Secretion in Pseudohypoparathyroidism - Full Text View

Study of the Regulation of Parathyroid Hormone Secretion in Pseudohypoparathyroidism

This study has been completed.

Sponsors and Collaborators:	National Center for Research Resources (NCRR) University of California, Los Angeles
Information provided by:	Office of Rare Diseases (ORD)
ClinicalTrials.gov Identifier:	NCT00004661

Purpose

OBJECTIVES:

Determine the relationship between serum calcium concentrations and parathyroid hormone secretion in patients with pseudohypoparathyroidism.

Condition

Pseudohypoparathyroidism

Drug Information available for:

Parathyroid

U.S. FDA Resources

Study Type:	Observational
Study Design:	Screening

Further study details as provided by Office of Rare Diseases (ORD):

Estimated Enrollment:	20
Study Start Date:	May 1993

Detailed Description:

PROTOCOL OUTLINE:

Patients are tested for parathyroid hormone response following sequential graded intravenous infusions of sodium citrate and calcium gluconate. Assays include ionized calcium and intact parathyroid hormone.

Eligibility

Ages Eligible for Study:	12 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

PROTOCOL ENTRY CRITERIA:

--Disease Characteristics-- Pseudohypoparathyroidism, i.e.: Renal resistance to parathyroid hormone OR Albright hereditary osteodystrophy No other illness unless related to pseudohypoparathyroidism No pregnant women

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00004661

Sponsors and Collaborators

National Center for Research Resources (NCRR)

University of California, Los Angeles

Investigators


Study Chair:	Mitchell E. Geffner	University of California, Los Angeles

More Information

Study ID Numbers:	199/11909, UCLA-541
First Received:	February 24, 2000
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00004661
Health Authority:	United States: Federal Government

Keywords provided by Office of Rare Diseases (ORD):

endocrine disorders

pseudohypoparathyroidism

rare disease

Study placed in the following topic categories:

Metabolism, Inborn Errors

Pseudohypoparathyroidism

Metabolic Diseases

Genetic Diseases, Inborn

Musculoskeletal Diseases

Rare Diseases

Endocrine System Diseases

Bone Diseases, Metabolic

Albright's hereditary osteodystrophy

Endocrinopathy

Metabolic disorder

Bone Diseases

Additional relevant MeSH terms:

Calcium Metabolism Disorders

Metal Metabolism, Inborn Errors

ClinicalTrials.gov processed this record on November 20, 2008