Characteristics of Idiopathic Familial Speech Disorders
According to studies, speech disorders with unknown causes (idiopathic) affect approximately 5% of the population at some point in their life. Some of these disorders like, stuttering and cluttering, are known for being detected early, during speech development.
Stuttering is characterized by sound and syllable repetitions and consonant/vowel prolongations. When stuttering is moderate to severe, it can interfere with a person's job and social activities.
Speech articulation disorders are characterized by omissions, or substitutions of speech sounds. The speech of a person who clutters is often difficult to understand. People are often unaware of the errors they make when speaking causing treatment of the condition to be very difficult.
The purpose of this research is to study an extended family whose members exhibit a pure form of speech articulation disorders
In addition, the study will use data and information gathered from the study and use it to develop guidelines (criteria) for defining and differentiating patients with speech disorders.
Developmental Articulation Disorder
|Official Title:||Characteristics of Idiopathic Familial Speech Disorders|
|Study Start Date:||May 1996|
|Primary Completion Date:||November 2009 (Final data collection date for primary outcome measure)|
Our objective is to determine which factors are involved in the development of stuttering and familial phonological processing disorder and are associated with a familial pattern of inheritance.
Study population: The study population is comprised of 8 groups:
- Children and adults with persistent developmental stuttering;
- Unaffected siblings of the individuals affected with developmental stuttering or recovered from stuttering
- Children and adults who have recovered from developmental stuttering;
- Children and adults with persistent familial phonological processing disorders (FPPD);
- Unaffected siblings of the individuals affected with FPPD or have recovered from FPPD
- Children and adults who have recovered from FPPD;
- Unaffected siblings of the individuals who have recovered from FPPD;
- Children and adults with normal speech and language development who will comprise the control groups.
Design: A Natural history design will be used to compare affected and unaffected family members with healthy volunteers with normal speech and language.
Outcome Measures: Genetic markers and pedigree analyses will be used to test familial inheritance patterns. Speech and language development will be compared using indices of speech perception, auditory perception, self monitoring of one's own speech, language complexity, motor complexity, speech learning, phonological processing and verbal/nonverbal memory.
|United States, Maryland|
|University of Maryland, College Park|
|College Park, Maryland, United States|
|United States, Wisconsin|
|University of Wisconsin|
|Madison, Wisconsin, United States, 53792|