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Magnetic Resonance Imaging Studies of Motor and Thought Processes
This study has been completed.
First Received: November 3, 1999   Last Updated: March 3, 2008   History of Changes
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Information provided by: National Institutes of Health Clinical Center (CC)
ClinicalTrials.gov Identifier: NCT00001361
  Purpose

Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation). MRI is especially useful when studying the brain, because it can provide information about certain brain functions. In addition, MRI is much better than standard X-rays at showing areas of the brain close to the skull and detecting changes in the brain associated with neurological diseases. In this study researchers will use MRI to gather information about the processes that control human movement and sensory processing.

The purpose of the study is to investigate how the brain is activated when remembering, thinking, or recognizing objects. Researchers would like to determine what happens to brain functions when patients have trouble remembering, thinking, or recognizing objects following the start of disorders in the brain and nervous system. In addition, this study will investigate the processes of motor control in healthy volunteers and patients with disease.


Condition
Cerebrovascular Disorder
Healthy
Movement Disorder
Nervous System Disease
Spinal Cord Injury

Study Type: Observational
Official Title: Central Nervous System Motor and Cognitive Processes: Nuclear Magnetic Resonance Imaging at 1.5 to 4 Tesla

Resource links provided by NLM:


Further study details as provided by National Institutes of Health Clinical Center (CC):

Estimated Enrollment: 610
Study Start Date: October 1992
Estimated Study Completion Date: January 2002
Detailed Description:

The main purpose of the studies presented in this protocol is to investigate the physiology of motor control in health as well as the pathophysiological modifications taking place during disease. Patients and normal volunteers will be scanned at rest and during different tasks, either while making repetitive movements or undergoing sensory stimulation. These studies should provide new insight concerning the processes that control human movement and sensory processing. The studies described in this protocol will be conducted by systems operating on 1.5 Tesla up to 4 Tesla, including a system at 3 Tesla which is going to be installed in near future.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Patients with movement disorder and normal volunteers.

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00001361

Locations
United States, Maryland
National Institute of Neurological Disorders and Stroke (NINDS)
Bethesda, Maryland, United States, 20892
Sponsors and Collaborators
  More Information

Publications:
Study ID Numbers: 930010, 93-N-0010
Study First Received: November 3, 1999
Last Updated: March 3, 2008
ClinicalTrials.gov Identifier: NCT00001361     History of Changes
Health Authority: United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):
Movement Disorders
Sensory Processing
Stroke
Spinal Cord Injury
Blood Flow
Blood Volume
Cognitive Function
Neurobehavioral Deficits
Neurological Disorders
Magnetic Resonance Imaging
Plasticity
Normal Volunteer

Additional relevant MeSH terms:
Disease
Spinal Cord Diseases
Nervous System Diseases
Vascular Diseases
Wounds and Injuries
Disorders of Environmental Origin
Central Nervous System Diseases
Trauma, Nervous System
Brain Diseases
Cerebrovascular Disorders
Spinal Cord Injuries
Pathologic Processes
Movement Disorders
Cardiovascular Diseases

ClinicalTrials.gov processed this record on November 05, 2009