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| Sponsored by: |
National Institute of Mental Health (NIMH) |
|---|---|
| Information provided by: | National Institutes of Health Clinical Center (CC) |
| ClinicalTrials.gov Identifier: | NCT00001360 |
Purpose
The purpose of this study is to use brain imaging technology to measure changes in blood flow to areas in the brain as individuals perform intellectual tasks.
This study will use functional magnetic resonance imaging (fMRI) to examine blood flow to areas of the brain as participants engage in tasks associated with visual perception, visual recognition, and memory.
| Condition |
|---|
|
Cognition Disorder Healthy |
Magnetic resonance imaging will be used to measure hemodynamic changes in healthy human subjects engaged in performing cognitive tasks. Specific questions concerning the location of the neural systems that mediate perceptual and semantic representations of objects and the spatial coordinate systems used for object localization will be addressed. The studies proposed here will be conducted only on normal adult men and women to examine the functional organization of the intact human brain.
Eligibility
Normal adults, with at least a high school education, aged 18 to 65 years, will be recruited to participate in the study.
EXCLUSION CRITERIA:
Subjects will be excluded if they have evidence of, or a history of, learning disability, psychiatric condition, head trauma, seizures or other neurological condition, alcoholism or substance abuse, hypertension, or cardiovascular disease.
We will also exclude subjects with vision and/or hearing problems severe enough to interfere with testing.
Females with a positive pregnancy test will be excluded from neuroimaging studies.
All subjects will be questioned prior to MRI scanning for possible occupational exposure to metal slivers or shavings, which may have become accidentally lodged in the tissues of the head or neck. Those whose history is suggestive of such a problem will be excluded. Subjects with surgical clips or shrapnel in or near the brain or blood vessels, subjects with cochlear implants, subjects with any metallic body in the eye or CNS, and subjects with any form of implant wire or metal device which may concentrate radiofrequency fields will be excluded because of possible risks during MRI scanning.
Contacts and Locations| Contact: Patient Recruitment and Public Liaison Office | (800) 411-1222 | prpl@mail.cc.nih.gov |
| Contact: TTY | 1-866-411-1010 |
| United States, Maryland | |
| Johns Hopkins University | Recruiting |
| Baltimore, Maryland, United States, 21205 | |
| National Institutes of Health Clinical Center, 9000 Rockville Pike | Recruiting |
| Bethesda, Maryland, United States, 20892 | |
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