Evaluating Pancreatic Tumors in Patients With Zollinger-Ellison Syndrome - Full Text View

Evaluating Pancreatic Tumors in Patients With Zollinger-Ellison Syndrome

This study is ongoing, but not recruiting participants.

Sponsored by:	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Information provided by:	National Institutes of Health Clinical Center (CC)
ClinicalTrials.gov Identifier:	NCT00001254

Purpose

This protocol concerns the approach to the localization, diagnosis of MEN1 and management of the tumor and the tissue samples in patients with Zollinger-Ellison syndrome. It details the diagnostic imaging tests to be used to localize the tumor, investigations for MEN1 the subsequent management of the tumor and tissue samples for research.

Condition

Gastrinoma
Zollinger Ellison Syndrome

MedlinePlus related topics:

Cancer

U.S. FDA Resources

Study Type:	Observational

Official Title:	Evaluation of the Gastrinoma in Patients With Zollinger-Ellison Syndrome

Further study details as provided by National Institutes of Health Clinical Center (CC):

Estimated Enrollment:	999
Study Start Date:	May 1990

Detailed Description:

This protocol concerns the localization and management of the tumor in patients with Zollinger-Ellison syndrome. It details the diagnostic imaging tests to be used to localize the tumor and the subsequent management of the tumor.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

INCLUSION CRITERIA:

New patients will be evaluated initially as described in the protocol entitled, "Diagnostic evaluation of patients with suspected abnormalities of gastric secretion" (89-DK-0005).

Only those patients that are being treated under the protocol entitled, "Medical Therapy of Zollinger-Ellison Syndrome" (protocol # 89-DK-0015) will be entered into this tumor localization and management protocol.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00001254

Locations


United States, Maryland
	National Institutes of Health Clinical Center, 9000 Rockville Pike
	Bethesda, Maryland, United States, 20892

Sponsors and Collaborators

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

More Information

NIH Clinical Center Detailed Web Page This link exits the ClinicalTrials.gov site

Publications:

Wolfe MM, Jensen RT. Zollinger-Ellison syndrome. Current concepts in diagnosis and management. N Engl J Med. 1987 Nov 5;317(19):1200-9. Review.

Andersen DK. Current diagnosis and management of Zollinger-Ellison syndrome. Ann Surg. 1989 Dec;210(6):685-703. Review.

Creutzfeldt W, Arnold R, Creutzfeldt C, Track NS. Pathomorphologic, biochemical, and diagnostic aspects of gastrinomas (Zollinger-Ellison syndrome). Hum Pathol. 1975 Jan;6(1):47-76.

Study ID Numbers:	900137, 90-DK-0137
First Received:	November 3, 1999
Last Updated:	July 18, 2008
ClinicalTrials.gov Identifier:	NCT00001254
Health Authority:	United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):

Islet Cell Tumors

Study placed in the following topic categories:

Digestive System Neoplasms

Gastrointestinal Diseases

Ulcer

Pancreatic Neoplasms

Carcinoma, Islet Cell

Endocrine System Diseases

Intestinal Diseases

Carcinoma

Stomach Diseases

Paraneoplastic Syndromes

Gastrinoma

Digestive System Diseases

Zollinger-Ellison Syndrome

Zollinger-Ellison syndrome

Gastrointestinal Neoplasms

Pancreatic Diseases

Endocrinopathy

Adenocarcinoma

Pancreatic islet cell tumors

Peptic Ulcer

Neoplasms, Glandular and Epithelial

Endocrine Gland Neoplasms

Additional relevant MeSH terms:

Neoplasms

Pathologic Processes

Disease

Neoplasms by Site

Neoplasms by Histologic Type

Syndrome

Paraneoplastic Endocrine Syndromes

ClinicalTrials.gov processed this record on September 05, 2008