IV Cocaine Abuse: A Laboratory Model - 2

This study has been completed.

First Received: September 20, 1999 Last Updated: June 23, 2005 History of Changes

Sponsor:	National Institute on Drug Abuse (NIDA)
Collaborator:	Columbia University
Information provided by:	National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier:	NCT00000213

Purpose

The purpose of this study is to evaluate the effects of fluoxetine maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving.

Condition	Intervention	Phase
Cocaine-Related Disorders	Drug: Fluoxetine	Phase II

Study Type:	Interventional
Study Design:	Treatment
Official Title:	IV Cocaine Abuse: A Laboratory Model

Resource links provided by NLM:

Drug Information available for: Cocaine hydrochloride Fluoxetine Fluoxetine hydrochloride

U.S. FDA Resources

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:

Direct cocaine effects
Interaction of cocaine/fluox. on cardio measures
Interaction of cocaine/fluox. on coc's subjective
Effects of fluoxetine on cocaine craving
Drug use during outpatient fluoxetine maintenance

Estimated Enrollment:	0
Study Start Date:	April 1990

Eligibility

Ages Eligible for Study:	18 Years to 45 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Please contact site for information.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000213

Locations

United States, New York
Columbia University
New York, New York, United States, 10023

Sponsors and Collaborators

National Institute on Drug Abuse (NIDA)

Columbia University

Investigators

Principal Investigator:

Richard Foltin, Ph.D.

Columbia University

More Information

No publications provided

Study ID Numbers:	NIDA-06234-2, R01-06234-2
Study First Received:	September 20, 1999
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00000213 History of Changes
Health Authority:	United States: Federal Government

Additional relevant MeSH terms:

Cocaine-Related Disorders
Neurotransmitter Uptake Inhibitors
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs
Psychotropic Drugs
Disorders of Environmental Origin
Serotonin Uptake Inhibitors
Pharmacologic Actions

Fluoxetine
Serotonin Agents
Mental Disorders
Therapeutic Uses
Substance-Related Disorders
Antidepressive Agents, Second-Generation
Central Nervous System Agents
Antidepressive Agents

ClinicalTrials.gov processed this record on November 09, 2009