39 studies found for:    xyrem
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Rank Status Study
1 Completed Trial of Xyrem for Excessive Daytime Sleepiness and Sleep Disturbance in Parkinson's Disease (PD)
Condition: Parkinson Disease
Intervention: Drug: sodium oxybate
2 Recruiting Study of the Symptomatic Effects of Nocturnal Sodium Oxybate in Parkinson's Disease
Condition: Sleep-wake Disturbances in Motor-phase Parkinson`s Disease
Intervention: Drug: Sodium Oxybate
3 Completed
Has Results
Trial Comparing Effects of Xyrem Taken Orally and Modafinil With Placebo in Treating Daytime Sleepiness in Narcolepsy
Condition: Narcolepsy
Interventions: Drug: Xyrem;   Drug: Xyrem Placebo;   Drug: Modafinil at established dose;   Drug: Modafinil (Placebo)
4 Withdrawn The Effect of Sodium Oxybate on Sleep Architecture
Condition: Mechanically Ventilated ICU Patients
Interventions: Drug: sodium oxybate;   Drug: placebo
5 Not yet recruiting Sodium Oxybate in Patients With Chronic Fatigue Syndrome.
Condition: Chronic Fatigue Syndrome
Interventions: Drug: Sodium oxybate;   Drug: Placebo
6 Completed Sodium Oxybate in Schizophrenia With Insomnia
Conditions: Schizophrenia;   Insomnia Associated to Schizophrenia
Intervention: Drug: Sodium Oxybate
7 Completed Exploratory Clinical Study to Evaluate Sodium Oxybate (Xyrem) on Potential Endocrine Changes
Condition: Narcolepsy With Cataplexy
Intervention: Drug: Sodium Oxybate (Xyrem)
8 Completed
Has Results
Trial Comparing the Effects of Xyrem (Sodium Oxybate) With Placebo for the Treatment of Fibromyalgia
Condition: Fibromyalgia
Interventions: Drug: Xyrem (sodium oxybate) oral solution;   Drug: Placebo
9 Completed Xyrem(Sodium Oxybate) and Ambien(Zolpidem Tartrate) in the Treatment of Chronic Insomnia.
Condition: Sleep Initiation and Maintenance Disorders
Interventions: Drug: zolpidem tartrate;   Drug: sodium oxybate;   Drug: Matching Placebos
10 Active, not recruiting A Phase 1, Single Dose Study of JZP-386 to Evaluate Safety, Pharmacokinetics and Pharmacodynamics
Condition: Narcolepsy, Excessive Daytime Sleepiness
Interventions: Drug: Placebo;   Drug: Sodium Oxybate;   Drug: JZP-386
11 Not yet recruiting A Multicenter Study of the Efficacy and Safety of Xyrem With an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects With Narcolepsy With Cataplexy
Condition: Narcolepsy With Cataplexy
Intervention: Drug: Xyrem
12 Terminated Use of Xyrem to Improve Sleep in Chronic Fatigue Syndrome
Condition: Chronic Fatigue Syndrome
Intervention: Drug: Xyrem [sodium oxybate]
13 Withdrawn Xyrem for Treatment Refractory Insomnia Due to PTSD
Conditions: PTSD;   Anxiety, Post Traumatic
Intervention: Drug: Xyrem
14 Completed Enhancing Slow Wave Sleep With Sodium Oxybate
Condition: Sleep
Intervention: Drug: sodium oxybate
15 Completed
Has Results
Trial of Effects of Oral Xyrem and Zolpidem on Sleep-Disordered Breathing in Obstructive Sleep Apnea Patients
Condition: Obstructive Sleep Apnea Syndrome
Interventions: Drug: Xyrem (X);   Drug: Zolpidem  (Z);   Drug: Modafinil (M);   Drug: Placebo (P)
16 Completed Comparative Study of Gamma-hydroxy Butyrate Versus Oxazepam in the Treatment of Alcohol Withdrawal Syndrome
Conditions: Alcohol Withdrawal Syndrome;   Alcohol Dependence
Interventions: Drug: Sodium Oxybate (SMO);   Drug: Oxazepam
17 Recruiting Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response
Conditions: Spasmodic Dysphonia;   Voice Tremor
Intervention: Drug: Sodium oxybate
18 Terminated Safety and Feasibility of Sodium Oxybate in Mild Alzheimer's Disease Patients
Condition: Mild Alzheimer's Disease
Intervention: Drug: Sodium Oxybate
19 Completed
Has Results
Sodium Oxybate in Patients With Alternating Hemiplegia of Childhood (AHC-SO)
Condition: Alternating Hemiplegia of Childhood
Intervention: Drug: Sodium Oxybate
20 Completed
Has Results
Safety and Tolerability Study Comparing Sodium Oxybate Given as an Oral Solution to a Single-blinded Combination of Oral Tablets Plus Oral Solution in Subjects With Fibromyalgia
Condition: Fibromyalgia
Interventions: Drug: Sodium Oxybate;   Drug: Sodium Oxybate & 6 Tablets;   Drug: Sodium Oxybate & 8 Tablets;   Drug: Sodium Oxybate Oral Solution (6 grams)

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Indicates status has not been verified in more than two years