40 studies found for:    pontine glioma
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Rank Status Study
1 Active, not recruiting PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Progressive or Refractory High-Grade Glioma
Intervention: Drug: Crenolanib
2 Recruiting Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Brainstem Glioma
Intervention:
3 Completed Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma
Condition: Recurrent Diffuse Pontine Gliomas
Intervention: Biological: nimotuzumab (anti EGFR humanized monoclonal antibody)
4 Recruiting Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Bevacizumab;   Drug: Erlotinib;   Drug: Temozolomide;   Radiation: Irradiation
5 Recruiting Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
Conditions: Diffuse Intrinsic Pontine Glioma;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Drug: Lenalidomide;   Radiation: Radiation Therapy
6 Completed
Has Results
A Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine Gliomas
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Procedure: adjuvant therapy;   Biological: pegylated interferon alfa
7 Terminated Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents
Condition: Gliomas
Interventions: Drug: Cilengitide;   Drug: Temozolomide
8 Recruiting Erivedge (Vismodegib) in the Treatment of Pediatric Patients With Refractory Pontine Glioma
Condition: Pontine Glioma
Intervention: Drug: Vismodegib
9 Recruiting Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)
Conditions: Diffuse Intrinsic Pontine Glioma;   High-grade Glioma
Intervention: Drug: Chemotherapy
10 Recruiting Imiquimod/Brain Tumor Initiating Cell (BTIC) Vaccine in Brain Stem Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Glioblastoma Multiforme;   Adult Glioblastoma
Interventions: Biological: Tumor Lysate Vaccine;   Drug: Imiquimod;   Radiation: Radiation therapy
11 Active, not recruiting A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas
Conditions: Newly Diagnosed High-Grade Gliomas;   Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan
12 Recruiting Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).
Condition: Diffuse Intrinsic Pontine Glioma (DIPG)
Intervention: Drug: Melphalan hydrochloride
13 Active, not recruiting Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG)
Condition: Diffuse Intrinsic Pontine Glioma
Intervention: Drug: vandetanib and dasatinib
14 Recruiting Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma and Relapsed Glioblastoma Multiforme
Condition: Malignant Gliomas
Intervention: Biological: CT-011
15 Recruiting Convection-Enhanced Delivery of 124I-8H9 for Patients With Non-Progressive Diffuse Pontine Gliomas Previously Treated With External Beam Radiation Therapy
Conditions: Brain Cancer;   Brain Stem Glioma
Intervention: Radiation: Radioactive iodine-labeled monoclonal antibody 8H9
16 Active, not recruiting Cilengitide in Combination With Irradiation in Children With Diffuse Intrinsic Pontine Glioma
Condition: Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Cilengitide dose escalation;   Drug: Cilengitide;   Radiation: Concomitant radiotherapy;   Biological: Pharmacokinetic;   Biological: Pharmacogenetic;   Biological: Exploratory investigation
17 Recruiting Palliative Re-irradiation for Progressive Diffuse Intrinsic Pontine Glioma (DIPG) in Children
Condition: Pediatric Malignant Brain Tumor -Diffuse Intrinsic Pontine Glioma
Intervention: Radiation: Palliative re-irradiation for progressive DIPG in children
18 Completed
Has Results
Motexafin Gadolinium and Radiation Therapy in Treating Young Patients With Pontine Glioma
Condition: Untreated Childhood Brain Stem Glioma
Interventions: Drug: motexafin gadolinium;   Radiation: 3-dimensional conformal radiation therapy
19 Terminated Phase I Rindopepimut After Conventional Radiation in Children w/ Diffuse Intrinsic Pontine Gliomas
Conditions: Brain Cancer;   Brain Stem Tumors;   Pontine Tumors
Intervention: Biological: Rindopepimut
20 Completed Nimotuzumab in Children With Intrinsic Pontine Glioma
Condition: Diffuse Instrinsic Ponitine Glioma
Intervention: Drug: nimotuzumab

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Indicates status has not been verified in more than two years