44 studies found for:    pediatric low grade gliomas
Show Display Options
Rank Status Study
1 Recruiting A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas
Condition: Brain Tumors
Intervention: Drug: Poly ICLC
2 Unknown  A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas
Conditions: Newly Diagnosed Pediatric Pontine Glioma.;   Newly Diagnosed Pediatric High Grade Glioma.;   Recurrent Pediatric High Grade Glioma.;   Recurrent Pediatric Low Grade Glioma.
Interventions: Biological: HLA-A2 restricted synthetic glioma antigen peptides vaccine;   Drug: Poly ICLC;   Genetic: Reverse transcriptase-polymerase chain reaction;   Other: enzyme-linked immunosorbent assay;   Other: flow cytometry;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis
3 Not yet recruiting Pilot Study of Mebendazole to Treat Pediatric Low-Grade Gliomas
Conditions: Pilomyxoid Astrocytoma;   Pilocytic Astrocytoma;   Glioma, Astrocytic;   Optic Nerve Glioma;   Pleomorphic Xanthoastrocytoma
Interventions: Drug: Mebendazole;   Drug: Vincristine;   Drug: Carboplatin;   Drug: Temozolomide
4 Recruiting AZD6244 in Children With Low-Grade Gliomas
Conditions: Optic Glioma;   Pilocytic Astrocytoma;   Low Grade Glioma;   Fibriullary Astrocytoma
Intervention: Drug: AZD6244
5 Recruiting Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
Conditions: Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Mixed Glioma;   Childhood Pilocytic Astrocytoma;   Neurofibromatosis Type 1;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Oligodendroglioma;   Recurrent Childhood Pilocytic Astrocytoma;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Recurrent Childhood Visual Pathway Glioma
Interventions: Drug: selumetinib;   Other: laboratory biomarker analysis;   Other: pharmacological study
6 Recruiting Vinorelbine for Children With Progressive or Recurrent Low-grade Gliomas
Condition: Low-grade Glioma
Intervention: Drug: Weekly vinorelbine treatment
7 Recruiting A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects
Condition: Neoplasms, Brain
Intervention: Drug: Dabrafenib
8 Recruiting PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
Conditions: Pediatric Recurrent Progressive Low-grade Gliomas;   Pediatric Progressive Low-grade Gliomas
Intervention: Drug: Everolimus
9 Active, not recruiting
Has Results
Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma
Conditions: Childhood High-grade Cerebral Astrocytoma;   Childhood Oligodendroglioma;   Childhood Spinal Cord Neoplasm;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma
Interventions: Biological: bevacizumab;   Drug: irinotecan hydrochloride;   Radiation: fludeoxyglucose F 18
10 Recruiting Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation
Conditions: Brain Tumor;   Low Grade Glioma;   Astrocytoma;   Ependymoma;   Ganglioglioma
Intervention: Radiation: Proton radiotherapy
11 Completed
Has Results
A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects
Conditions: Central Nervous System Tumors;   Brain Tumors
Intervention: Procedure: Radiation Therapy
12 Completed Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas
Conditions: Glioma;   Low-grade Glioma
Intervention: Drug: RAD001
13 Active, not recruiting Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs)
Condition: Glioma
Intervention: Drug: Vinblastine Sulphate
14 Recruiting Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults
Conditions: Refractory Low-grade Gliomas;   Recurrent Low-grade Gliomas
Interventions: Drug: Vinblastine + Nilotinib;   Drug: Vinblastine
15 Recruiting Study Of Vinblastine in Combination With Nilotinib in Children, Adolescents and Young Adults
Conditions: Refractory Low-grade Gliomas;   Recurrent Low-grade Gliomas
Interventions: Drug: Nilotinib;   Drug: Vinblastine
16 Active, not recruiting Radiation Therapy in Treating Young Patients With Gliomas
Conditions: Brain Tumor;   Central Nervous System Tumor
Intervention: Radiation: radiation therapy
17 Unknown  Magnetic Resonance Imaging in Treating Children With Progressive Low-Grade Astrocytoma
Condition: Brain and Central Nervous System Tumors
Interventions: Procedure: conventional surgery;   Procedure: magnetic resonance spectroscopic imaging;   Radiation: radiation therapy
18 Active, not recruiting MicroRNAs in Patients With Neurofibromatosis Type 1
Conditions: Glioma;   Neurofibromatosis Type 1
Intervention:
19 Unknown  Study of Busulfan for Refractory Central Nervous System (CNS) Tumors
Condition: Refractory Brain Tumors
Intervention: Drug: Busulfan
20 Not yet recruiting Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations
Condition: Cancer
Interventions: Drug: Trametinib;   Drug: Dabrafenib

Previous Page Studies Shown (1-20) Next Page (21-40) Show next page of results
Indicates status has not been verified in more than two years