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46 studies found for:    pediatric low grade gliomas
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Rank Status Study
1 Recruiting A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas
Condition: Brain Tumors
Intervention: Drug: Poly ICLC
2 Unknown  A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas
Conditions: Newly Diagnosed Pediatric Pontine Glioma.;   Newly Diagnosed Pediatric High Grade Glioma.;   Recurrent Pediatric High Grade Glioma.;   Recurrent Pediatric Low Grade Glioma.
Interventions: Biological: HLA-A2 restricted synthetic glioma antigen peptides vaccine;   Drug: Poly ICLC;   Genetic: Reverse transcriptase-polymerase chain reaction;   Other: enzyme-linked immunosorbent assay;   Other: flow cytometry;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis
3 Not yet recruiting Pilot Study of Mebendazole to Treat Pediatric Low-Grade Gliomas
Conditions: Pilomyxoid Astrocytoma;   Pilocytic Astrocytoma;   Glioma, Astrocytic;   Optic Nerve Glioma;   Pleomorphic Xanthoastrocytoma
Interventions: Drug: Mebendazole;   Drug: Vincristine;   Drug: Carboplatin;   Drug: Temozolomide
4 Recruiting Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
Conditions: Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Mixed Glioma;   Childhood Pilocytic Astrocytoma;   Neurofibromatosis Type 1;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Oligodendroglioma;   Recurrent Childhood Pilocytic Astrocytoma;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Recurrent Childhood Visual Pathway Glioma
Interventions: Drug: selumetinib;   Other: laboratory biomarker analysis;   Other: pharmacological study
5 Recruiting AZD6244 in Children With Low-Grade Gliomas
Conditions: Optic Glioma;   Pilocytic Astrocytoma;   Low Grade Glioma;   Fibriullary Astrocytoma
Intervention: Drug: AZD6244
6 Active, not recruiting Vinorelbine for Children With Progressive or Recurrent Low-grade Gliomas
Condition: Low-grade Glioma
Intervention: Drug: Weekly vinorelbine treatment
7 Recruiting A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects
Condition: Neoplasms, Brain
Intervention: Drug: Dabrafenib
8 Recruiting PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
Conditions: Pediatric Recurrent Progressive Low-grade Gliomas;   Pediatric Progressive Low-grade Gliomas
Intervention: Drug: Everolimus
9 Active, not recruiting
Has Results
Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma
Conditions: Childhood High-grade Cerebral Astrocytoma;   Childhood Oligodendroglioma;   Childhood Spinal Cord Neoplasm;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma
Interventions: Biological: bevacizumab;   Drug: irinotecan hydrochloride;   Radiation: fludeoxyglucose F 18
10 Not yet recruiting MEK 162 for Children w/Progressive/Recurrent Cancer/Study for Children w/Low-Grade Gliomas/Other Ras/Raf/MAP Pathway Activated Tumors
Conditions: Progressive or Recurrent Cancer;   Low-Grade Gliomas;   Ras/Raf/MAP Pathway Activated Tumors
Intervention: Drug: MEK162
11 Recruiting Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation
Conditions: Brain Tumor;   Low Grade Glioma;   Astrocytoma;   Ependymoma;   Ganglioglioma
Intervention: Radiation: Proton radiotherapy
12 Completed
Has Results
A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects
Conditions: Central Nervous System Tumors;   Brain Tumors
Intervention: Procedure: Radiation Therapy
13 Completed Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas
Conditions: Glioma;   Low-grade Glioma
Intervention: Drug: RAD001
14 Active, not recruiting Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs)
Condition: Glioma
Intervention: Drug: Vinblastine Sulphate
15 Recruiting Study Of Vinblastine in Combination With Nilotinib in Children, Adolescents and Young Adults
Conditions: Refractory Low-grade Gliomas;   Recurrent Low-grade Gliomas
Interventions: Drug: Nilotinib;   Drug: Vinblastine
16 Recruiting Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults
Conditions: Refractory Low-grade Gliomas;   Recurrent Low-grade Gliomas
Interventions: Drug: Vinblastine + Nilotinib;   Drug: Vinblastine
17 Active, not recruiting Radiation Therapy in Treating Young Patients With Gliomas
Conditions: Brain Tumor;   Central Nervous System Tumor
Intervention: Radiation: radiation therapy
18 Unknown  Magnetic Resonance Imaging in Treating Children With Progressive Low-Grade Astrocytoma
Condition: Brain and Central Nervous System Tumors
Interventions: Procedure: conventional surgery;   Procedure: magnetic resonance spectroscopic imaging;   Radiation: radiation therapy
19 Active, not recruiting MicroRNAs in Patients With Neurofibromatosis Type 1
Conditions: Glioma;   Neurofibromatosis Type 1
Intervention:
20 Unknown  Study of Busulfan for Refractory Central Nervous System (CNS) Tumors
Condition: Refractory Brain Tumors
Intervention: Drug: Busulfan

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