Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
1911 studies found for:    neoplasms [CONDITION] AND child [AGE-GROUP] | Open Studies
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Rank Status Study
21 Recruiting Gallium Ga 68-Edotreotide PET/CT Compared With Indium In 111 Pentetreotide Plus Contrast-Enhanced CT (or MRI) in Diagnosing Patients With Neuroendocrine Tumors and Other Somatostatin Receptor Positive Tumors
Conditions: Adult Medulloblastoma;   Childhood Medulloblastoma;   Neuroblastoma;   Neuroendocrine Tumor;   Somatostatinoma
Interventions: Radiation: gallium Ga 68-edotreotide;   Procedure: positron emission tomography/computed tomography;   Radiation: indium In 111 pentetreotide;   Procedure: computed tomography;   Procedure: contrast-enhanced magnetic resonance imaging
22 Unknown  Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas
Conditions: Colorectal Neoplasms;   Stomach Neoplasms;   Pancreatic Neoplasms;   Breast Neoplasms;   Ovarian Cancer
Intervention:
23 Recruiting Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex
Conditions: Cushing's Syndrome;   Hereditary Neoplastic Syndrome;   Lentigo;   Neoplasm;   Testicular Neoplasm
Intervention:
24 Not yet recruiting NAC to Prevent Cisplatin-induced Hearing Loss
Conditions: Neuroectodermal Tumors, Primitive;   Liver Neoplasms;   Neoplasms, Germ Cell and Embryonal;   Osteosarcoma;   Other Childhood Cancers Using Cisplatin-based Regimens
Intervention: Drug: N-Acetylcysteine
25 Unknown  Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors
Conditions: Brain and Central Nervous System Tumors;   Extragonadal Germ Cell Tumor;   Ovarian Cancer;   Testicular Germ Cell Tumor
Interventions: Biological: filgrastim;   Biological: lenograstim;   Biological: pegfilgrastim;   Drug: cisplatin;   Drug: gemcitabine hydrochloride;   Drug: ifosfamide;   Drug: paclitaxel
26 Unknown  Studies of Temozolomide in Combination With Topotecan in Refractory and Relapsed Paediatric Solid Tumours
Conditions: Neuroblastoma;   Brain Tumors;   Solid Tumors
Intervention: Drug: Temozolomide/Hycamtin (Topotecan)
27 Unknown  ESTD vs. VATS for Upper Gastrointestinal Submucosal Tumors
Conditions: Upper Gastrointestinal Submucosal Tumors (SMTs);   Gastrointestinal Stromal Tumors (GISTs);   Leiomyoma
Interventions: Procedure: ESTD;   Procedure: VATS
28 Recruiting Prospective Assessment of Quality of Life (QOL) in Pediatric Patients Treated With Radiation Therapy for Brain Tumors and Non-central Nervous System (Non-CNS) Malignancies
Conditions: Brain Tumors;   Non-CNS Malignancies
Intervention: Other: Quality of Life surveys completed at specified timepoints
29 Unknown  Biomarker Study in Samples From Patients With Malignant Rhabdoid Tumor of the Kidney or Atypical Teratoid Rhabdoid Tumor
Conditions: Brain and Central Nervous System Tumors;   Kidney Cancer
Interventions: Genetic: RNA analysis;   Genetic: gene expression analysis;   Genetic: polymerase chain reaction;   Genetic: protein expression analysis;   Other: laboratory biomarker analysis
30 Unknown  Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor Progression
Conditions: Childhood Germ Cell Tumor;   Extragonadal Germ Cell Tumor;   Ovarian Cancer;   Testicular Germ Cell Tumor
Interventions: Genetic: DNA methylation analysis;   Genetic: mutation analysis;   Genetic: nucleic acid sequencing;   Genetic: polymerase chain reaction;   Genetic: polymorphism analysis;   Other: laboratory biomarker analysis;   Other: medical chart review
31 Recruiting Holmium-166-radioembolization in NET After Lutetium-177-dotatate; an Efficacy Study
Condition: Neuroendocrine Tumor (NET) Liver Metastases
Intervention: Device: Holmium-166 microspheres hepatic radioembolization.
32 Recruiting Study of Denosumab in Subjects With Giant Cell Tumor of Bone
Conditions: Cancer;   GCT;   Giant Cell Tumor of Bone;   Benign GCT
Intervention: Drug: Denosumab
33 Recruiting Study of Kidney Tumors in Young Patients
Conditions: Clear Cell Sarcoma of the Kidney;   Congenital Mesoblastic Nephroma;   Diffuse Hyperplastic Perilobar Nephroblastomatosis;   Rhabdoid Tumor of the Kidney;   Stage I Renal Cell Cancer;   Stage I Wilms Tumor;   Stage II Renal Cell Cancer;   Stage II Wilms Tumor;   Stage III Renal Cell Cancer;   Stage III Wilms Tumor;   Stage IV Renal Cell Cancer;   Stage IV Wilms Tumor;   Stage V Wilms Tumor
Interventions: Other: laboratory biomarker analysis;   Other: cytology specimen collection procedure
34 Recruiting Biomarkers in Tissue Samples From Patients With High-Risk Wilms Tumor
Conditions: Clear Cell Sarcoma of the Kidney;   Recurrent Wilms Tumor and Other Childhood Kidney Tumors;   Rhabdoid Tumor of the Kidney;   Stage I Wilms Tumor;   Stage II Wilms Tumor;   Stage III Wilms Tumor;   Stage IV Wilms Tumor;   Stage V Wilms Tumor
Interventions: Genetic: DNA methylation analysis;   Genetic: gene expression analysis;   Genetic: microarray analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: diagnostic laboratory biomarker analysis
35 Recruiting Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors
Conditions: Glioma;   Brain Cancer;   Brain Tumor;   Glioblastoma Multiforme;   High Grade Glioma
Interventions: Biological: Dendritic Cell Vaccine;   Biological: Tumor Lysate;   Other: Imiquimod;   Procedure: Punch Biopsy of the Skin;   Procedure: Leukapheresis
36 Recruiting Molecular Markers in Treatment in Endometrial Cancer
Conditions: Endometrial Neoplasms;   Neoplasm Metastasis
Intervention: Procedure: Tumor biopsy study
37 Recruiting Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
Conditions: Adult Supratentorial Primitive Neuroectodermal Tumor (PNET);   Childhood Supratentorial Primitive Neuroectodermal Tumor;   Ewing Sarcoma of Bone;   Extraosseous Ewing Sarcoma;   Extraosseous Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Peripheral Primitive Neuroectodermal Tumor of the Kidney;   Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions: Drug: vincristine sulfate;   Drug: doxorubicin hydrochloride;   Drug: cyclophosphamide;   Drug: ifosfamide;   Drug: etoposide;   Drug: topotecan hydrochloride;   Other: laboratory biomarker analysis
38 Recruiting Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor;   Childhood Central Nervous System Germ Cell Tumor;   Childhood Choroid Plexus Tumor;   Childhood Craniopharyngioma;   Childhood Grade I Meningioma;   Childhood Grade II Meningioma;   Childhood Grade III Meningioma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Oligodendroglioma;   Childhood Supratentorial Ependymoma;   Newly Diagnosed Childhood Ependymoma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Recurrent Childhood Visual Pathway Glioma
Intervention: Other: cytology specimen collection procedure
39 Recruiting Collecting and Storing Biological Samples From Patients With Ewing Sarcoma
Conditions: Askin Tumor;   Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Intervention: Other: laboratory biomarker analysis
40 Recruiting Study of Stored Tumor Samples in Young Patients With Brain Tumors
Condition: Brain and Central Nervous System Tumors
Intervention:

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