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236 studies found for:    heart transplant | United States, Delaware | United States, New Jersey | United States, Pennsylvania

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Rank Status Study
1 Recruiting Heartsbreath Test for Heart Transplant Rejection
Condition: Heart Transplant Rejection
Intervention:
2 Completed A Study of Safety, Tolerability & Efficacy of Certican in de Novo Heart Transplant (Tx) Patients
Condition: Heart Transplantation
Intervention: Drug: Everolimus (Certican)
3 Completed
Has Results 		Study Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant Recipients
Conditions: Graft Rejection;   Kidney Failure
Interventions: Drug: cyclosporine or tacrolimus;   Drug: sirolimus
4 Recruiting Allo-antibodies in Pediatric Heart Transplantation
Condition: Pediatric Heart Transplantation
Interventions: Drug: Induction Therapy (anti-T cell antibody induction);   Drug: Tacrolimus (Prograf);   Drug: Mycophenolate Mofetil- MMF (CellCept);   Procedure: Intraoperative plasma exchange/pheresis;   Procedure: Short-term post-operative plasmapheresis;   Drug: Post-transplant course of intravenous immunoglobulin (IVIG) therapy.;   Drug: Prednisone
5 Completed
Has Results 		Efficacy and Safety of Everolimus in Recipients of Heart Transplants to Prevent Acute and Chronic Rejection
Condition: Graft Rejection
Interventions: Drug: everolimus;   Drug: mycophenolate mofetil;   Drug: cyclosporine;   Drug: corticosteroids
6 Recruiting Outcomes AlloMap Registry: the Long-term Management and Outcomes of Heart Transplant Recipients With AlloMap Testing
Conditions: Cardiac Transplant Failure;   Cardiac Transplant Rejection;   Heart Diseases
Intervention:
7 Completed Noninvasive Methods to Monitor Graft Survival in Heart Transplant Patients
Condition: Cardiac Transplant
Intervention: Procedure: Heart transplant
8 Recruiting Prevention of Cardiac Allograft Vasculopathy Using Rituximab (Rituxan) Therapy in Cardiac Transplantation
Condition: Cardiac Allograft Vasculopathy
Interventions: Biological: Rituximab induction/conventional immunosuppression (tacrolimus, MMF, and steroid taper);   Drug: Rituximab placebo/conventional immunosuppression (tacrolimus, MMF, and steroid taper)
9 Unknown † VentrAssistTM LVAD as a Bridge to Cardiac Transplantation - Pivotal Trial
Conditions: End-stage Heart Failure;   Cardiomyopathies
Intervention: Device: VentrAssistTM Left Ventricular Assist Device
10 Terminated Thymic Tolerance in Pediatric Heart Transplantation
Condition: Heart Transplantation
Intervention: Procedure: donor bone marrow cell injection into thymus gland
11 Not yet recruiting Safety and Efficacy of Desensitization Therapy in Sensitized Participants Awaiting Heart Transplantation
Conditions: Transplantation;   Organ Transplantation;   Heart Transplantation
Interventions: Drug: Bortezomib;   Procedure: Plasmapheresis on days 0, 1 and 2.
12 Terminated Heart Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Heart Transplant Recipients
Condition: Heart Transplantation
Intervention: Drug: mycophenolate mofetil [CellCept]; sirolimus [Rapamune]
13 Completed
Has Results 		Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Bridge to Cardiac Transplantation
Conditions: Heart Failure, Congestive;   Ventricular Dysfunction;   Cardiomyopathies
Intervention: Device: Thoratec HeartMate II Left Ventricular Assist System (LVAS)
14 Completed Validating PROMIS Instruments in Congestive Heart Failure Patients Receiving a Heart Transplant
Condition: Congestive Heart Failure
Intervention:
15 Unknown † Safety Outcomes of Lower Immunosuppression Versus Traditional Immunosuppression in Heart Transplant Recipients
Condition: Heart Transplantation
Interventions: Drug: Tacrolimus;   Drug: mycophenolate mofetil therapy
16 Recruiting Endothelial Injury and Development of Coronary Intimal Thickening After Heart Transplantation
Conditions: Cardiac Allograft Vasculopathy;   Antibody Mediated Rejection
Interventions: Device: Optical Coherence Tomography;   Drug: Acetylcholine;   Procedure: Brachial Artery Flow Mediated Dilation
17 Terminated The Epidemiology of Bleeding and Clotting in Patients Undergoing Heart Transplantation, Coronary Artery Bypass Graft Surgery,or Implantation of Left Ventricular Assist Devices
Condition: Congestive Heart Failure
Intervention:
18 Completed Safety/Efficacy of Everolimus and Neoral® in Adult Cardiac Transplant Patients With Established Allograft Vasculopathy
Condition: Graft Rejection
Intervention: Drug: everolimus
19 Terminated Evaluation of the Safety and Effectiveness of the DuraHeart™ LVAS
Condition: Heart Failure
Intervention: Device: DuraHeart Left Ventricular Assist System (LVAS)
20 Completed VentrAssistTM LVAD as a Bridge to Cardiac Transplantation - Feasibility Trial
Conditions: End-Stage Heart Failure;   Cardiomyopathies
Intervention: Device: VentrAssist Left Ventricular Assist Device
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† Indicates status has not been verified in more than two years