439 studies found for:    glioma | Open Studies
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glioma | Open Studies (439 records)
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Rank Status Study
1 Recruiting A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas
Conditions: Newly Diagnosed High-Grade Gliomas;   Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan
2 Recruiting Identification of Clinically Occult Glioma Cells and Characterization of Glioma Behavior Through Machine Learning Analysis of Advanced Imaging Technology
Condition: Glioma
Interventions: Procedure: MRS Imaging;   Procedure: PET Scanning;   Procedure: Diffusion Tensor Imaging
3 Recruiting A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas
Conditions: Newly Diagnosed Pediatric Pontine Glioma.;   Newly Diagnosed Pediatric High Grade Glioma.;   Recurrent Pediatric High Grade Glioma.;   Recurrent Pediatric Low Grade Glioma.
Interventions: Biological: HLA-A2 restricted synthetic glioma antigen peptides vaccine;   Drug: Poly ICLC;   Genetic: Reverse transcriptase-polymerase chain reaction;   Other: enzyme-linked immunosorbent assay;   Other: flow cytometry;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis
4 Recruiting Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Brainstem Glioma
Intervention:
5 Recruiting Gene Expression, Immunological Status and Metabolome in Glioma Patients
Condition: Glioma
Interventions: Procedure: Glioma resection;   Other: Blood sampling
6 Recruiting Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents
Condition: Gliomas
Interventions: Drug: Cilengitide;   Drug: Temozolomide
7 Recruiting PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Progressive or Refractory High-Grade Glioma
Intervention: Drug: Crenolanib
8 Recruiting Blood Flow MRI for Monitoring Brain Tumors
Condition: Brain Tumors
Intervention:
9 Recruiting Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
Conditions: Diffuse Intrinsic Pontine Glioma;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Drug: Lenalidomide;   Radiation: Radiation Therapy
10 Recruiting Low-Dose Naltrexone for Glioma Patients
Condition: Malignant Glioma
Interventions: Drug: Naltrexone;   Other: Placebo
11 Recruiting An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma
Conditions: Brain Neoplasm;   Glioma
Intervention: Drug: IL13-PE38QQR
12 Recruiting Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)
Conditions: Diffuse Intrinsic Pontine Glioma;   High-grade Glioma
Intervention: Drug: Chemotherapy
13 Recruiting AZD6244 in Children With Low-Grade Gliomas
Conditions: Optic Glioma;   Pilocytic Astrocytoma;   Low Grade Glioma;   Fibriullary Astrocytoma
Intervention: Drug: AZD6244
14 Recruiting Lenalidomide and Radiation Therapy in Treating Young Patients With Pontine Glioma or High-Grade Glioma
Conditions: Childhood Choroid Plexus Tumor;   Childhood Grade III Meningioma;   Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Mixed Glioma;   Childhood Oligodendroglioma;   Childhood Supratentorial Ependymoma;   Newly Diagnosed Childhood Ependymoma;   Untreated Childhood Brain Stem Glioma;   Untreated Childhood Subependymal Giant Cell Astrocytoma;   Untreated Childhood Visual Pathway and Hypothalamic Glioma;   Untreated Childhood Visual Pathway Glioma
Interventions: Drug: lenalidomide;   Radiation: radiation therapy;   Other: laboratory biomarker analysis;   Other: pharmacological study
15 Not yet recruiting Pilot Study of Mebendazole to Treat Pediatric Low-Grade Gliomas
Conditions: Pilomyxoid Astrocytoma;   Pilocytic Astrocytoma;   Glioma, Astrocytic;   Optic Nerve Glioma;   Pleomorphic Xanthoastrocytoma
Interventions: Drug: Mebendazole;   Drug: Vincristine;   Drug: Carboplatin;   Drug: Temozolomide
16 Recruiting Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma
Conditions: Adult Anaplastic Astrocytoma;   Adult Anaplastic Ependymoma;   Adult Anaplastic Oligodendroglioma;   Adult Brain Stem Glioma;   Adult Diffuse Astrocytoma;   Adult Ependymoma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Adult Myxopapillary Ependymoma;   Adult Oligodendroglioma;   Adult Pilocytic Astrocytoma;   Adult Pineal Gland Astrocytoma;   Adult Subependymal Giant Cell Astrocytoma;   Adult Subependymoma
Interventions: Procedure: biopsy;   Procedure: computed tomography;   Procedure: therapeutic conventional surgery;   Radiation: radiation therapy treatment planning/simulation;   Radiation: radiation therapy;   Procedure: magnetic resonance imaging;   Procedure: positron emission tomography;   Drug: fluorine F 18 fluorodopa
17 Not yet recruiting Dendritic Cell Vaccine For Malignant Glioma and Glioblastoma Multiforme in Adult and Pediatric Subjects
Conditions: Malignant Glioma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Biological: Dendritic Cell Vaccine;   Biological: Tumor Lysate;   Other: Imiquimod;   Procedure: Leukapheresis
18 Unknown  Correlation Between SV2A Expression in Tumour Tissue and Efficacy of Levetiracetam in Glioma Patients With Epilepsy
Conditions: Epilepsy;   Glioma
Intervention:
19 Not yet recruiting Re-irradiation of High Grade Gliomas: a Quality of Life Study
Conditions: Anaplastic Astrocytoma;   Glioblastoma Multiforme;   Anaplastic Oligoastrocytoma
Interventions: Other: EORTC QLQ-C30;   Other: EORTC QLQ-BN20;   Other: Hopkins Verbal Learning Test-Revised (HVLT-R);   Other: Stroop color-word test;   Other: Controlled oral word association test (COWA);   Other: Jamar hand dynamometer;   Other: EORTC QLQ- FA13;   Other: Trail Making Test (TMT)
20 Recruiting Study of RAD001 (Everolimus) for Children With NF1 and Chemotherapy-Refractory Radiographic Progressive Low Grade Gliomas
Condition: Glioma
Intervention: Drug: RAD001 (Everolimus)

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