230 studies found for:    glioblastoma | Recruiting | Interventional Studies
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1 Recruiting Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma
Conditions: Glioblastoma;   Glioblastoma Multiforme;   Glioma;   Astrocytoma;   Brain Tumor
Interventions: Biological: Dendritic cell vaccination, in addition to standard temozolomide chemotherapy and involved field radiation therapy;   Biological: Dendritic cell vaccination, with optional bevacizumab treatment for patients previously treated with bevacizumab
2 Recruiting Ketogenic Diet as Adjunctive Treatment in Refractory/End-stage Glioblastoma Multiforme: a Pilot Study
Condition: Glioblastoma Multiforme
Intervention: Other: ketogenic diet
3 Recruiting Safety and Tolerability of Carboxyamidotriazole Orotate (CTO) in Solid Tumors or With Temodar® in Glioblastoma or Other Recurrent Malignant Gliomas or in Combination With Temodar® and Radiation Therapy for Patients With Newly Diagnosed Glioblastoma and Malignant Gliomas
Condition: Solid Tumors, Glioblastoma, Recurrent Malignant Gliomas
Interventions: Drug: CTO;   Drug: CTO and Temodar®;   Drug: CTO, Temodar®, Radiation therapy
4 Recruiting NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Biological: Bevacizumab;   Device: NovoTTF-l00A;   Other: Quality of Life Assessment
5 Recruiting Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma
Conditions: Glioblastoma;   Small Cell Glioblastoma;   Giant Cell Glioblastoma;   Gliosarcoma;   Glioblastoma With Oligodendroglial Component
Interventions: Drug: Rindopepimut (CDX-110) with GM-CSF;   Drug: Temozolomide;   Drug: KLH
6 Recruiting Amgen 386 for Recurrent Glioblastoma
Condition: Glioblastoma Multiforme
Interventions: Drug: Amgen 386;   Drug: Bevacizumab
7 Recruiting A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
Conditions: Glioblastoma;   Small Cell Glioblastoma;   Giant Cell Glioblastoma;   Gliosarcoma;   Glioblastoma With Oligodendroglial Component;   Recurrent Glioblastoma;   Relapsed Glioblastoma
Interventions: Drug: Bevacizumab;   Drug: Rindopepimut (CDX-110) with GM-CSF;   Drug: KLH
8 Recruiting Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma
Conditions: Giant Cell Glioblastoma;   Glioblastoma;   Gliosarcoma
Interventions: Biological: bevacizumab;   Drug: temozolomide;   Other: laboratory biomarker analysis;   Other: immunohistochemistry staining method;   Genetic: microarray analysis;   Genetic: DNA methylation analysis
9 Recruiting Phase II Pazopanib Plus Topotecan for Recurrent Glioblastoma Multiforme (GBM)
Conditions: Brain Neoplasms;   Central Nervous System Neoplasms
Interventions: Drug: Pazopanib;   Drug: Topotecan;   Behavioral: Symptom Questionnaire;   Behavioral: Phone Calls
10 Unknown  Prolonged Adjuvant Temozolomide vs "Stop & Go" in Glioblastoma Patients
Condition: Glioblastoma
Intervention: Drug: Temozolomide
11 Recruiting WEE1 Inhibitor MK-1775, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Drug: WEE1 inhibitor MK-1775;   Radiation: radiation therapy;   Drug: temozolomide;   Other: pharmacological study;   Other: laboratory biomarker analysis
12 Recruiting Efficacy, Safety and CNS Exposure of G-202 in Patients With Recurrent or Progressive Glioblastoma
Conditions: Recurrent Glioblastoma;   Progressive Glioblastoma
Intervention: Drug: G-202
13 Recruiting BrUOG 263: Prostate Specific Membrane Antigen (PSMA) Glioblastoma Multiforme (GBM)
Conditions: GBM;   Glioblastoma Multiforme;   Gliosarcoma
Intervention: Drug: PSMA ADC
14 Recruiting A Study of Subcutaneous Bevacizumab in Relapsed / Progressive Glioblastoma
Condition: Glioblastoma
Intervention: Drug: Bevacizumab 25 mg in 1 ml subcutaneously daily
15 Recruiting A Explore Study of Bevacizumab Combined With Conventional Therapy in Glioblastoma
Condition: Glioblastoma
Interventions: Other: Chemoradiation Therapy;   Other: Adjuvant Therapy
16 Recruiting PI/II of Temozolomide & Hypofractionated Radiotherapy in Tx of Supratentorial Glioblastoma Multiform
Conditions: Glioblastoma;   Cancer of Brain and Nervous System;   Glioblastoma Multiforme
Interventions: Drug: Temozolomide;   Procedure: Stereotactic Radiosurgery
17 Recruiting Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme
Conditions: Adult Brain Glioblastoma;   Glioblastoma Multiforme
Interventions: Biological: SL-701; Imiquimod Cream 5%; Leukine 150 micrograms;   Drug: Imiquimod Cream 5%;   Drug: Leukine 150 micrograms
18 Recruiting Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)
Conditions: Brain Cancer;   Glioblastoma Multiforme
Interventions: Drug: Vorinostat;   Drug: Erlotinib;   Drug: Temozolomide
19 Recruiting Procarbazine and Lomustine in Recurrent Glioblastoma
Condition: Recurrent Glioblastoma Multiforme
Intervention: Drug: lomustine and procarbazine
20 Recruiting Virus DNX2401 and Temozolomide in Recurrent Glioblastoma
Conditions: Glioblastoma Multiforme;   Recurrent Tumor
Intervention: Procedure: DNX2401 and Temozolomide

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Indicates status has not been verified in more than two years