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197 studies found for:    glioblastoma | Recruiting | Interventional Studies

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1 Recruiting Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma
Conditions: Glioblastoma;   Small Cell Glioblastoma;   Giant Cell Glioblastoma;   Gliosarcoma;   Glioblastoma With Oligodendroglial Component
Interventions: Drug: Rindopepimut (CDX-110) with GM-CSF;   Drug: Temozolomide;   Drug: KLH
2 Recruiting A Study of PD 0332991 in Patients With Recurrent Rb Positive Glioblastoma
Conditions: Glioblastoma;   Gliosarcoma;   Anaplastic Astrocytoma
Intervention: Drug: PD 0332991
3 Recruiting Amgen 386 for Recurrent Glioblastoma
Condition: Glioblastoma Multiforme
Interventions: Drug: Amgen 386;   Drug: Bevacizumab
4 Recruiting A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
Conditions: Glioblastoma;   Small Cell Glioblastoma;   Giant Cell Glioblastoma;   Gliosarcoma;   Glioblastoma With Oligodendroglial Component;   Recurrent Glioblastoma;   Relapsed Glioblastoma
Interventions: Drug: Bevacizumab;   Drug: Rindopepimut (CDX-110) with GM-CSF;   Drug: KLH
5 Recruiting A Study of Onartuzumab (MetMAb) in Combination With Bevacizumab Compared to Bevacizumab Alone or Onartuzumab Monotherapy in Patients With Recurrent Glioblastoma
Condition: Glioblastoma
Interventions: Drug: onartuzumab;   Drug: bevacizumab;   Drug: onartuzumab placebo;   Drug: bevacizumab placebo
6 Recruiting Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma
Conditions: Giant Cell Glioblastoma;   Glioblastoma;   Gliosarcoma
Interventions: Biological: bevacizumab;   Drug: temozolomide;   Other: laboratory biomarker analysis;   Other: immunohistochemistry staining method;   Genetic: microarray analysis;   Genetic: DNA methylation analysis
7 Unknown † Prolonged Adjuvant Temozolomide vs "Stop & Go" in Glioblastoma Patients
Condition: Glioblastoma
Intervention: Drug: Temozolomide
8 Recruiting A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma
Conditions: Glioblastoma Multiforme;   Glioma;   Astrocytoma;   Brain Tumor
Intervention: Drug: Intrathecal liposomal Ara-C + Temozolomide
9 Recruiting PI/II of Temozolomide & Hypofractionated Radiotherapy in Tx of Supratentorial Glioblastoma Multiform
Conditions: Glioblastoma;   Cancer of Brain and Nervous System;   Glioblastoma Multiforme
Interventions: Drug: Temozolomide;   Procedure: Stereotactic Radiosurgery
10 Recruiting TRC105 for Recurrent Glioblastoma
Condition: Glioblastoma Multiforme
Intervention: Drug: TRC105
11 Recruiting Radiosurgery Plus Bevacizumab in Glioblastoma
Conditions: Glioblastoma;   Gliosarcoma;   Brain Tumor
Interventions: Radiation: radiosurgery;   Biological: bevacizumab;   Drug: irinotecan hydrochloride
12 Recruiting Procarbazine and Lomustine in Recurrent Glioblastoma
Condition: Recurrent Glioblastoma Multiforme
Intervention: Drug: lomustine and procarbazine
13 Recruiting Peptide-based Glioma Vaccine IMA950 in Patients With Glioblastoma
Condition: Glioblastoma
Interventions: Drug: Cyclophosphamide;   Biological: IMA950 plus GM-CSF;   Biological: IMA950;   Drug: Imiquimod
14 Recruiting Phase III Study Comparing 2 Brain Conformational Radiotherapy in Combination With Chemotherapy in the Treatment of Glioblastoma
Condition: Glioblastoma
Interventions: Radiation: Radiotherapy;   Radiation: Experimental arm
15 Recruiting Gliadel Wafer and Fluorescence-Guided Surgery With 5-ALA Followed by Radiation Therapy And Temozolomide in Treating Patients With Primary Glioblastoma
Condition: Glioblastoma
Interventions: Drug: 5-ALA;   Drug: Gliadel wafers
16 Recruiting Bi-weekly Temozolomide Plus Bevacizumab for Adult Patients With Recurrent Glioblastoma Multiforme
Conditions: Recurrent Glioblastoma Multiforme;   Recurrent Gliosarcoma
Intervention: Drug: temozolomide and bevacizumab
17 Recruiting Vandetanib and Sirolimus in Patients With Recurrent Glioblastoma
Condition: Glioblastoma
Interventions: Drug: Sirolimus;   Drug: Vandetanib
18 Recruiting Parvovirus H-1 (ParvOryx) in Patients With Progressive Primary or Recurrent Glioblastoma Multiforme.
Condition: Glioblastoma Multiforme
Intervention: Drug: H-1PV
19 Recruiting Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma
Interventions: Drug: cediranib maleate;   Drug: temozolomide;   Other: placebo;   Radiation: intensity-modulated radiation therapy;   Radiation: 3-dimensional conformal radiation therapy;   Procedure: magnetic resonance spectroscopic imaging;   Procedure: dynamic contrast-enhanced magnetic resonance imaging;   Other: fluorine F 18 fluorothymidine;   Procedure: positron emission tomography;   Other: laboratory biomarker analysis
20 Recruiting Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma
Condition: Glioblastoma Multiforme/Anaplastic Astrocytoma
Interventions: Drug: temozolomide;   Radiation: radiation therapy;   Radiation: stereotactic radiotherapy
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† Indicates status has not been verified in more than two years