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Found 63 studies with search of: familial hypercholesterolemia
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Rank Status Study
1 Completed Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia
Conditions: Heterozygous Familial Hypercholesterolemia;   Mixed Dyslipidemia
Intervention: Drug: Fluvastatin
2 Enrolling by invitation Long Term, Follow-on Study of Lomitapide in Patients With Homozygous Familial Hypercholesterolemia
Condition: Familial Hypercholesterolemia
Intervention: Drug: lomitapide
3 Withdrawn Effect of APL180 on Endothelial Function in Familial Hypercholesterolemia Patients
Condition: Familial Hypercholesterolemia
Interventions: Drug: APL180;   Drug: Placebo
4 Terminated Implitapide in Patients With Homozygous Familial Hypercholesterolemia (HoFH) on Maximal Concurrent Lipid-Lowering Therapy
Condition: Familial Hypercholesterolemia
Intervention: Drug: Implitapide
5 Terminated Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy
Condition: Familial Hypercholesterolemia
Intervention: Drug: Implitapide
6 Recruiting Evaluation of Chylomicrons Metabolism in Sub-Clinical Atherosclerosis in Patients Whit Heterozigous Familial Hypercholesterolemia (FH) Treated With Statin Plus Ezetimibe
Condition: Heterozigous Familial Hypercholesterolemia
Intervention: Drug: Statins and Ezetimibe
7 Completed Study to Assess the Safety and Efficacy of ISIS 301012 in Homozygous Familial Hypercholesterolemia
Conditions: Lipid Metabolism, Inborn Errors;   Hypercholesterolemia, Autosomal Dominant;   Hyperlipidemias;   Metabolic Diseases;   Hyperlipoproteinemia Type II;   Metabolism, Inborn Errors;   Genetic Diseases, Inborn;   Infant, Newborn, Diseases;   Metabolic Disorder;   Congenital Abnormalities;   Hypercholesterolemia;   Hyperlipoproteinemias;   Dyslipidemias;   Lipid Metabolism Disorders
Interventions: Drug: mipomersen sodium;   Drug: Placebo
8 Active, not recruiting Open Label Extension of ISIS 301012 to Treat Familial Hypercholesterolemia
Conditions: Lipid Metabolism, Inborn Errors;   Hypercholesterolemia, Autosomal Dominant;   Hyperlipidemias;   Metabolic Diseases;   Hyperlipoproteinemia Type II;   Metabolism, Inborn Errors;   Genetic Diseases, Inborn;   Infant, Newborn, Diseases;   Metabolic Disorder;   Congenital Abnormalities;   Hypercholesterolemia;   Hyperlipoproteinemias;   Dyslipidemias;   Lipid Metabolism Disorders
Intervention: Drug: mipomersen sodium
9 Completed Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial Hypercholesterolemia
Condition: Familial Hypercholesterolemia
Intervention: Procedure: gene therapy
10 Enrolling by invitation An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia
Conditions: Lipid Metabolism, Inborn Errors;   Hypercholesterolemia, Autosomal Dominant;   Hyperlipidemias;   Metabolic Diseases;   Hyperlipoproteinemia Type II;   Metabolism, Inborn Errors;   Genetic Diseases, Inborn;   Infant, Newborn, Diseases;   Metabolic Disorder;   Congenital Abnormalities;   Hypercholesterolemia;   Hyperlipoproteinemias;   Dyslipidemias;   Lipid Metabolism Disorders
Intervention: Drug: mipomersen sodium
11 Completed 8-Week PK/PD Atorvastatin Study In Children And Adolescents With Heterozygous Familial Hypercholesterolemia
Condition: Hypercholesterolemia, Familial
Intervention: Drug: Atorvastatin
12 Recruiting Atorvastatin Three Year Pediatric Study
Condition: Familial Hypercholesterolemia
Intervention: Drug: atorvastatin
13 Completed Study of ISIS 301012 in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy
Condition: Hypercholesterolemia, Familial
Intervention: Drug: ISIS 301012 or Placebo
14 Completed Dose-Escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy
Condition: Hypercholesterolemia, Familial
Intervention: Drug: ISIS 301012
15 Active, not recruiting Efficacy and Safety Study of 301012 as Add-on in Familial Hypercholesterolemic Subjects With Coronary Artery Disease
Conditions: Heterozygous Familial Hypercholesterolemia;   Coronary Artery Disease
Interventions: Drug: mipomersen sodium;   Drug: placebo
16 Completed A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-on Therapy to Their Existing Medication
Condition: Familial Hypercholesterolemia
Interventions: Drug: Colesevelam hydrochloride film-coated tablets;   Drug: Placebo
17 Not yet recruiting Soy Food Intervention Trial
Condition: Familial Hypercholesterolemia
Interventions: Dietary Supplement: soy protein diet;   Dietary Supplement: rapeseed oil
18 Recruiting A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: AEGR-733
19 Completed Bone Marrow Stem Cells as a Source of Allogenic Hepatocyte Transplantation in Homozygous Familial Hypercholesterolemia
Condition: Hypercholesterolemia, Familial
Intervention: Procedure: Cellular transplantation
20 Recruiting Effect of Rapeseed Oil and Sunflower Oil
Condition: Familial Hypercholesterolemia
Interventions: Dietary Supplement: rapeseed oil;   Dietary Supplement: sunflower oil

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