47 studies found for:    eye diseases AND university of iowa | Exclude Unknown
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Rank Status Study
1 Recruiting Teprotumumab Treatment in Patients With Active Thyroid Eye Disease
Conditions: Thyroid Associated Ophthalmopathies;   Thyroid-Associated Ophthalmopathy
Interventions: Drug: teprotumumab;   Drug: Placebo
2 Completed
Has Results
Age-Related Eye Disease Study 2 (AREDS2)
Conditions: Age-related Macular Degeneration;   Cataract
Interventions: Dietary Supplement: Lutein/zeaxanthin;   Dietary Supplement: DHA/EPA;   Drug: Lutein/zeaxanthin and DHA/EPA
3 Recruiting Safety and Efficacy Study in Subjects With Leber Congenital Amaurosis
Condition: Inherited Retinal Dystrophy Due to RPE65 Mutations
Intervention: Biological: AAV2-hRPE65v2
4 No longer available Treatment of Patients With Age-Related Macular Degeneration With Anecortave Acetate
Condition: Macular Degeneration
Intervention: Drug: Anecortave Acetate
5 Recruiting Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors
Conditions: Acoustic Schwannoma;   Adult Anaplastic Astrocytoma;   Adult Anaplastic Ependymoma;   Adult Anaplastic Meningioma;   Adult Anaplastic Oligodendroglioma;   Adult Brain Stem Glioma;   Adult Choroid Plexus Tumor;   Adult Craniopharyngioma;   Adult Diffuse Astrocytoma;   Adult Ependymoblastoma;   Adult Ependymoma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Grade I Meningioma;   Adult Grade II Meningioma;   Adult Medulloblastoma;   Adult Meningeal Hemangiopericytoma;   Adult Mixed Glioma;   Adult Myxopapillary Ependymoma;   Adult Oligodendroglioma;   Adult Papillary Meningioma;   Adult Pilocytic Astrocytoma;   Adult Pineal Gland Astrocytoma;   Adult Pineoblastoma;   Adult Pineocytoma;   Adult Subependymal Giant Cell Astrocytoma;   Adult Subependymoma;   Adult Supratentorial Primitive Neuroectodermal Tumor (PNET);   Childhood Choroid Plexus Tumor;   Childhood Craniopharyngioma;   Childhood Ependymoblastoma;   Childhood Grade I Meningioma;   Childhood Grade II Meningioma;   Childhood Grade III Meningioma;   Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Medulloepithelioma;   Childhood Supratentorial Ependymoma;   Meningeal Melanocytoma;   Newly Diagnosed Childhood Ependymoma;   Recurrent Adult Brain Tumor;   Recurrent Childhood Anaplastic Astrocytoma;   Recurrent Childhood Anaplastic Oligoastrocytoma;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Diffuse Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Fibrillary Astrocytoma;   Recurrent Childhood Gemistocytic Astrocytoma;   Recurrent Childhood Giant Cell Glioblastoma;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Gliomatosis Cerebri;   Recurrent Childhood Gliosarcoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Oligoastrocytoma;   Recurrent Childhood Oligodendroglioma;   Recurrent Childhood Pilocytic Astrocytoma;   Recurrent Childhood Pilomyxoid Astrocytoma;   Recurrent Childhood Pineoblastoma;   Recurrent Childhood Pleomorphic Xanthoastrocytoma;   Recurrent Childhood Protoplasmic Astrocytoma;   Recurrent Childhood Subependymal Giant Cell Astrocytoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Recurrent Childhood Visual Pathway Glioma;   Untreated Childhood Anaplastic Astrocytoma;   Untreated Childhood Anaplastic Oligodendroglioma;   Untreated Childhood Brain Stem Glioma;   Untreated Childhood Cerebellar Astrocytoma;   Untreated Childhood Cerebral Astrocytoma;   Untreated Childhood Diffuse Astrocytoma;   Untreated Childhood Fibrillary Astrocytoma;   Untreated Childhood Gemistocytic Astrocytoma;   Untreated Childhood Giant Cell Glioblastoma;   Untreated Childhood Glioblastoma;   Untreated Childhood Gliomatosis Cerebri;   Untreated Childhood Gliosarcoma;   Untreated Childhood Medulloblastoma;   Untreated Childhood Oligoastrocytoma;   Untreated Childhood Oligodendroglioma;   Untreated Childhood Pilocytic Astrocytoma;   Untreated Childhood Pilomyxoid Astrocytoma;   Untreated Childhood Pineoblastoma;   Untreated Childhood Pleomorphic Xanthoastrocytoma;   Untreated Childhood Protoplasmic Astrocytoma;   Untreated Childhood Subependymal Giant Cell Astrocytoma;   Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor;   Untreated Childhood Visual Pathway and Hypothalamic Glioma;   Untreated Childhood Visual Pathway Glioma
Interventions: Radiation: gallium Ga 68-edotreotide;   Procedure: positron emission tomography;   Procedure: computed tomography;   Other: laboratory biomarker analysis
6 Completed Computer Detection of Diabetic Retinopathy Compared to Clinical Examination
Condition: Diabetic Retinopathy
Interventions: Procedure: Photography of the retina;   Procedure: Retinal photography
7 Active, not recruiting Surfactant Positive Airway Pressure and Pulse Oximetry Trial
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Bronchopulmonary Dysplasia;   Retinopathy of Prematurity;   Continuous Positive Airway Pressure
Interventions: Procedure: Early surfactant;   Procedure: Continuous Positive Airway Pressure (CPAP);   Procedure: Target oxygen saturation of 85-89%;   Procedure: Target oxygen saturation of 91-85%
8 Recruiting Inositol to Reduce Retinopathy of Prematurity
Condition: Retinopathy of Prematurity (ROP)
Intervention: Drug: myo-Inositol 5% Injection
9 Completed
Has Results
Confocal Analysis of Corneal Structures of Symptomatic Allergic Conjunctivitis Patients
Condition: Allergic Conjunctivitis
Intervention: Drug: Olopatadine hydrochloride ophthalmic solution, 0.2%
10 Completed Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2)
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Retinopathy of Prematurity;   Bronchopulmonary Dysplasia (BPD)
Interventions: Drug: Inositol lower volume;   Drug: Inositol mid-level volume;   Drug: Inositol high volume;   Drug: Placebo low volume
11 Active, not recruiting Diabetic Retinopathy in HIV Subjects Treated With EGRIFTA®
Conditions: Diabetic Retinopathy;   HIV
Interventions: Drug: Tesamorelin;   Drug: Placebo-Control
12 Completed Complications of Age-Related Macular Degeneration Prevention Trial
Condition: Macular Degeneration
Intervention: Procedure: Low-Intensity Laser Treatment
13 Recruiting Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Melanoma of the Eye
Conditions: Ciliary Body and Choroid Melanoma, Medium/Large Size;   Ciliary Body and Choroid Melanoma, Small Size;   Iris Melanoma;   Metastatic Intraocular Melanoma;   Recurrent Intraocular Melanoma;   Stage IIIA Intraocular Melanoma;   Stage IIIB Intraocular Melanoma;   Stage IIIC Intraocular Melanoma;   Stage IV Intraocular Melanoma
Interventions: Drug: cabozantinib-s-malate;   Drug: temozolomide;   Drug: dacarbazine;   Other: laboratory biomarker analysis
14 Active, not recruiting Temozolomide or Selumetinib in Treating Patients With Metastatic Melanoma of the Eye
Conditions: Ciliary Body and Choroid Melanoma, Medium/Large Size;   Ciliary Body and Choroid Melanoma, Small Size;   Iris Melanoma;   Metastatic Intraocular Melanoma;   Recurrent Intraocular Melanoma
Interventions: Drug: selumetinib;   Drug: temozolomide;   Other: laboratory biomarker analysis;   Other: quality-of-life assessment
15 Recruiting A Multi-Center, Randomized, Controlled Evaluation of the Safety and Efficacy of the KXL System With VibeX (Riboflavin Ophthalmic Solution) for Corneal Collagen Cross-Linking in Eyes With Keratoconus or Corneal Ectasia After Refractive Surgery
Conditions: Keratoconus;   Corneal Ectasia
Interventions: Device: KXL System (15 mW/cm2);   Device: KXL System (30 mW/cm2);   Device: KXL System (45 mW/cm2);   Drug: riboflavin ophthalmic solution
16 Completed Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis
Conditions: Multiple Sclerosis;   Optic Neuritis;   Transverse Myelitis;   Acute Brainstem/Cerebellar Syndrome
Intervention: Drug: interferon beta 1a 30 ug IM once weekly
17 Recruiting Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma
Condition: Extraocular Retinoblastoma
Interventions: Procedure: autologous bone marrow transplantation;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: in vitro-treated peripheral blood stem cell transplantation;   Drug: cisplatin;   Drug: cyclophosphamide;   Drug: etoposide;   Biological: filgrastim;   Drug: carboplatin;   Drug: vincristine sulfate;   Drug: thiotepa;   Radiation: radiation therapy
18 Active, not recruiting Phase I Dose Escalation Safety Study of RetinoStat in Advanced Age-Related Macular Degeneration (AMD)
Condition: Age Related Macular Degeneration
Intervention: Drug: 3 dose cohorts gene therapy
19 Active, not recruiting Cornea Preservation Time Study
Conditions: Cornea Preservation Time;   Endothelial Keratoplasty;   Transplant Success;   Endothelial Cell Density
Intervention: Biological: Cornea tissue transplant
20 Active, not recruiting
Has Results
Comparison of Age-related Macular Degeneration Treatments Trials: Lucentis-Avastin Trial
Condition: Age Related Macular Degeneration
Interventions: Drug: ranibizumab;   Drug: bevacizumab

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