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47 studies found for:    dira

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Rank Status Study
1 Recruiting Rilonacept for Deficiency of the Interleukin-1 Receptor Antagonist (DIRA)
Condition: DIRA
Intervention: Drug: Rilonacept
2 Recruiting IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions
Condition: Anterior Cruciate Ligament (ACL) Tears
Interventions: Drug: Kineret or placebo;   Drug: Kineret then Placebo;   Drug: Kineret;   Drug: Placebo
3 Completed Topical IL-1-Ra for Treatment of Corneal Neovascularization
Condition: Corneal Neovascularization
Interventions: Drug: Placebo;   Drug: IL-1Ra
4 Completed
Has Results 		Topical IL-1-Ra for Treatment of Posterior Blepharitis
Condition: Posterior Blepharitis
Interventions: Drug: 2.5% IL-1Ra;   Drug: Placebo;   Drug: 5% IL-1Ra
5 Completed Treatment of Patients With Type 2 Diabetes With an Interleukin-1 Antagonist
Condition: Type 2 Diabetes
Intervention: Drug: IL-1Ra
6 Recruiting Studies of the Natural History and Pathogenesis and Outcome of Neonatal Onset Multisystem Inflammatory Disease (NOMID/CAPS, DIRA, CRMO, Still's Disease, Behcet's Disease, and Other Undifferentiated Autoinflammatory Diseases)
Conditions: Urticaria;   Arthropathy;   Lymphadenopathy;   Nervous System Anomalies
Intervention:
7 Not yet recruiting Inflammation in Chronic Kidney Disease and Cardiovascular Disease - The Role of Genetics and Interleukin-1 Receptor Antagonist (IL-1ra)
Conditions: Chronic Kidney Disease;   Cardiovascular Disease
Interventions: Drug: Rilonacept;   Drug: Placebo
8 Recruiting Kinetic of Cytokines Decrease and Hodgkin Lymphoma Prognostic
Condition: Hodgkin's Disease
Intervention: Other: Collection of blood specimen
9 Recruiting Role of Interleukin-1 in the Regulation of Muscle Derived Interleukin-6 During Exercise
Condition: Type 2 Diabetes
Interventions: Drug: IL-1Ra;   Drug: Placebo
10 Completed Study to Prevent Cartilage Damage Following Acute Knee Injury.
Condition: Knee Injury
Intervention: Drug: Anakinra
11 Terminated The SPECTRA Study
Condition: Rheumatoid Arthritis
Interventions: Drug: anakinra;   Drug: anakinra and PEG sTNF-R1
12 Completed
Has Results 		A Study To Evaluate The Mechanism Of Action Of CP-690,550 In Patients With Rheumatoid Arthritis
Condition: Rheumatoid Arthritis
Interventions: Drug: CP-690,550 + methotrexate;   Drug: Placebo + Methotrexate
13 Completed Interleukin-1 Receptor Antagonist (IL-1RA) (ANAKINRA) IN SEVERE SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS
Condition: Systemic-Onset Juvenile Idiopathic Arthritis
Interventions: Drug: Anakinra;   Biological: Pneumo23
14 Completed Investigating Cytokine Genes of Stem Cell Donors
Condition: Stem Cell Transplantation
Intervention:
15 Completed Interleukin-1 Receptor Antagonist Gene Polymorphism and Adverse Pregnancy Outcome in Turkish Women
Condition: Periodontitis
Intervention:
16 Completed Study of Autologous Conditioned Serum After Anterior Cruciate Ligament Reconstructive Surgery
Condition: Joint Instability
Intervention: Procedure: ACL reconstructive surgery and ACS/ Orthokin application
17 Completed
Has Results 		Inflammation, Proteolysis and IL-1 Beta Receptor Inhibition in Chronic Hemodialysis Patients
Condition: End Stage Renal Disease
Interventions: Drug: kineret;   Drug: placebo
18 Completed
Has Results 		Anakinra With or Without Dexamethasone in Treating Patients With Smoldering or Indolent Multiple Myeloma
Condition: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: Biological: Anakinra (IL-1Ra);   Drug: Dexamethasone acetate
19 Recruiting Clinical Protocol Validation to Identify Prognostic Markers for Critical Care Pediatric Patients
Conditions: Electric Impedance;   Metabolic Expenditure and Respiratory Function.;   Polymorphisms Determinations of the Genes for TNF-alfa(-863 e -308), IL-1ra, LTalfa, IL-6, MIF e IL10.;   Cytokines Measurement;   NF-kappa B Activation.
Intervention:
20 Completed Anti-Interleukin-1 in Diabetes Action
Condition: Type 1 Diabetes
Interventions: Drug: anakinra;   Drug: saline
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† Indicates status has not been verified in more than two years