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13 studies found for:    dimebon | huntington
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Rank Status Study
1 Completed A Safety and Efficacy Study of Dimebon in Patients With Huntington Disease
Condition: Huntington Disease
Interventions: Drug: Dimebon;   Other: Placebo
2 Completed A Study of the Novel Drug Dimebon in Patients With Huntington's Disease
Condition: Huntington's Disease
Interventions: Other: Placebo;   Drug: Dimebon
3 Completed Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's Disease
Condition: Huntington's Disease
Intervention: Drug: Dimebon
4 Completed An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington Disease
Condition: Huntington Disease
Intervention: Drug: Dimebon (latrepirdine)
5 Completed A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)
Conditions: Alzheimer's Disease;   Huntington Disease
Interventions: Drug: Dimebon IR Tablet;   Drug: Dimebon MR1;   Drug: Dimebon MR2;   Drug: Dimebon MR3;   Drug: Dimebon MR4
6 Completed A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Dimebon alone;   Drug: Dimebon + Ketoconazole;   Drug: Dimebon + Omeprazole
7 Completed A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Warfarin;   Drug: Dimebon
8 Completed A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Dimebon IR;   Drug: Dimebon Transdermal
9 Completed Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects
Conditions: Alzheimer Disease;   Huntington Disease
Interventions: Drug: digoxin;   Drug: dimebon
10 Completed A Phase 1 Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF-01913539] In Japanese And Western Healthy Subjects
Conditions: Alzheimer's Disease;   Huntington's Disease
Intervention: Drug: Dimebon
11 Completed
Has Results
A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine) In Healthy Recreational Polydrug Users
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: dimebon;   Drug: placebo;   Drug: alprazolam
12 Completed A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function
Conditions: Alzheimer's Disease;   Huntington's Disease
Intervention: Drug: Dimebon
13 Completed A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of Dextromethorphan
Conditions: Huntington Disease;   Alzheimer Disease
Interventions: Drug: Dextromethorphan;   Drug: Dimebon + Dextromethorphan

Indicates status has not been verified in more than two years