897 studies found for:    cancer | wake forest
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21 Recruiting Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy
Conditions: Lymphedema;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer
Interventions: Procedure: Axillary Lymph Node Dissection;   Radiation: Nodal Radiation Therapy;   Radiation: Axillary Radiation Therapy
22 Recruiting Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor;   Childhood Central Nervous System Germ Cell Tumor;   Childhood Choroid Plexus Tumor;   Childhood Craniopharyngioma;   Childhood Grade I Meningioma;   Childhood Grade II Meningioma;   Childhood Grade III Meningioma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Oligodendroglioma;   Childhood Supratentorial Ependymoma;   Newly Diagnosed Childhood Ependymoma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Recurrent Childhood Visual Pathway Glioma
Intervention: Other: cytology specimen collection procedure
23 Active, not recruiting VTX-2337 and Pegylated Liposomal Doxorubicin (PLD) in Patients With Recurrent or Persistent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Conditions: Epithelial Ovarian Cancer;   Fallopian Tube Cancer;   Primary Peritoneal Cancer
Interventions: Drug: pegylated liposomal doxorubicin (PLD);   Drug: VTX-2337;   Drug: Placebo
24 Recruiting Carboplatin, Paclitaxel and Gemcitabine With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer
Conditions: Brenner Tumor;   Fallopian Tube Cancer;   Ovarian Clear Cell Cystadenocarcinoma;   Ovarian Endometrioid Adenocarcinoma;   Ovarian Mixed Epithelial Carcinoma;   Ovarian Mucinous Cystadenocarcinoma;   Ovarian Serous Cystadenocarcinoma;   Ovarian Undifferentiated Adenocarcinoma;   Primary Peritoneal Cavity Cancer;   Recurrent Ovarian Epithelial Cancer
Interventions: Drug: paclitaxel;   Drug: docetaxel;   Drug: carboplatin;   Biological: bevacizumab;   Drug: gemcitabine hydrochloride;   Other: laboratory biomarker analysis;   Other: quality-of-life assessment
25 Recruiting Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer
Conditions: Estrogen Receptor-positive Breast Cancer;   HER2-negative Breast Cancer;   Progesterone Receptor-positive Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Drug: systemic chemotherapy;   Drug: tamoxifen citrate;   Drug: anastrozole;   Drug: exemestane;   Drug: letrozole;   Other: laboratory biomarker analysis;   Other: quality-of-life assessment
26 Active, not recruiting Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)
Conditions: Estrogen Receptor-positive Breast Cancer;   HER2-negative Breast Cancer;   Progesterone Receptor-positive Breast Cancer;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage IIA Breast Cancer;   Stage IIB Breast Cancer;   Stage IIIB Breast Cancer
Interventions: Drug: tamoxifen citrate;   Drug: anastrozole;   Drug: letrozole;   Drug: exemestane;   Radiation: radiation therapy;   Other: laboratory biomarker analysis;   Other: quality-of-life assessment
27 Completed Fulvestrant With or Without Lapatinib in Treating Postmenopausal Women With Stage III or Stage IV Breast Cancer That is Hormone Receptor-Positive
Conditions: Recurrent Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer;   Stage IV Breast Cancer
Interventions: Drug: lapatinib ditosylate;   Drug: fulvestrant;   Other: placebo;   Other: laboratory biomarker analysis
28 Active, not recruiting Pemetrexed and/or Sunitinib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Conditions: Recurrent Non-small Cell Lung Cancer;   Stage IIIB Non-small Cell Lung Cancer;   Stage IV Non-small Cell Lung Cancer
Interventions: Drug: sunitinib malate;   Drug: pemetrexed disodium
29 Terminated
Has Results
Paclitaxel, Carboplatin, and Panitumumab in Treating Patients With Metastatic Breast Cancer
Conditions: Breast Cancer;   Recurrent Breast Cancer;   Stage IV Breast Cancer
Interventions: Biological: panitumumab;   Drug: paclitaxel;   Drug: carboplatin;   Procedure: laboratory biomarker analysis;   Procedure: immunohistochemistry staining method
30 Active, not recruiting Paclitaxel, Nab-paclitaxel, or Ixabepilone With or Without Bevacizumab in Treating Patients With Stage IIIC or Stage IV Breast Cancer
Conditions: Estrogen Receptor-negative Breast Cancer;   Estrogen Receptor-positive Breast Cancer;   HER2-negative Breast Cancer;   HER2-positive Breast Cancer;   Male Breast Cancer;   Progesterone Receptor-negative Breast Cancer;   Progesterone Receptor-positive Breast Cancer;   Recurrent Breast Cancer;   Stage IIIC Breast Cancer;   Stage IV Breast Cancer
Interventions: Drug: paclitaxel;   Drug: paclitaxel albumin-stabilized nanoparticle formulation;   Drug: ixabepilone;   Biological: bevacizumab;   Other: questionnaire administration;   Other: laboratory biomarker analysis
31 Active, not recruiting Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors
Conditions: Childhood Embryonal Tumor;   Childhood Extracranial Germ Cell Tumor;   Childhood Extragonadal Germ Cell Tumor;   Childhood Malignant Ovarian Germ Cell Tumor;   Childhood Malignant Testicular Germ Cell Tumor;   Childhood Teratoma;   Ovarian Embryonal Carcinoma;   Ovarian Yolk Sac Tumor;   Stage II Malignant Testicular Germ Cell Tumor;   Stage IIA Ovarian Germ Cell Tumor;   Stage IIB Ovarian Germ Cell Tumor;   Stage IIC Ovarian Germ Cell Tumor;   Stage III Malignant Testicular Germ Cell Tumor;   Stage IIIA Ovarian Germ Cell Tumor;   Stage IIIB Ovarian Germ Cell Tumor;   Stage IIIC Ovarian Germ Cell Tumor;   Testicular Choriocarcinoma and Yolk Sac Tumor;   Testicular Embryonal Carcinoma
Interventions: Procedure: conventional surgery;   Drug: cisplatin;   Drug: etoposide;   Biological: bleomycin sulfate;   Other: laboratory biomarker analysis
32 Completed Tamoxifen Citrate or Letrozole With or Without Bevacizumab in Treating Women With Stage III or Stage IV Breast Cancer
Conditions: Recurrent Breast Cancer;   Stage IIIB Breast Cancer;   Stage IV Breast Cancer
Interventions: Drug: tamoxifen citrate;   Drug: letrozole;   Biological: bevacizumab;   Other: laboratory biomarker analysis;   Other: questionnaire administration
33 Recruiting Radiation Therapy With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer
Condition: Head and Neck Cancer
Interventions: Biological: cetuximab;   Radiation: intensity-modulated radiation therapy
34 Recruiting Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab With or Without Estrogen Deprivation in Treating Patients With Hormone Receptor-Positive, HER2-Positive Operable or Locally Advanced Breast Cancer
Conditions: Estrogen Receptor-positive Breast Cancer;   HER2-positive Breast Cancer;   Progesterone Receptor-positive Breast Cancer;   Stage IB Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Drug: docetaxel;   Drug: carboplatin;   Biological: trastuzumab;   Biological: pertuzumab;   Drug: goserelin acetate;   Procedure: therapeutic conventional surgery;   Radiation: whole breast irradiation;   Other: laboratory biomarker analysis;   Drug: aromatase inhibition therapy;   Other: quality-of-life assessment
35 Active, not recruiting Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer
Conditions: Hereditary Non-polyposis Colon Cancer;   Mucinous Adenocarcinoma of the Colon;   Signet Ring Adenocarcinoma of the Colon;   Stage IIA Colon Cancer;   Stage IIB Colon Cancer;   Stage IIC Colon Cancer
Interventions: Drug: oxaliplatin;   Drug: leucovorin calcium;   Drug: fluorouracil;   Biological: bevacizumab;   Other: laboratory biomarker analysis
36 Recruiting Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor
Conditions: Brain and Central Nervous System Tumors;   Cognitive/Functional Effects;   Fatigue;   Neurotoxicity;   Psychosocial Effects of Cancer and Its Treatment
Interventions: Drug: modafinil;   Other: placebo
37 Active, not recruiting Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer
Conditions: Stage I Ovarian Epithelial Cancer;   Stage I Primary Peritoneal Cavity Cancer;   Stage IA Fallopian Tube Cancer;   Stage IB Fallopian Tube Cancer;   Stage IC Fallopian Tube Cancer;   Stage II Ovarian Epithelial Cancer;   Stage II Primary Peritoneal Cavity Cancer;   Stage IIA Fallopian Tube Cancer;   Stage IIB Fallopian Tube Cancer;   Stage IIC Fallopian Tube Cancer;   Stage III Ovarian Epithelial Cancer;   Stage III Primary Peritoneal Cavity Cancer;   Stage IIIA Fallopian Tube Cancer;   Stage IIIB Fallopian Tube Cancer;   Stage IIIC Fallopian Tube Cancer;   Stage IV Fallopian Tube Cancer;   Stage IV Ovarian Epithelial Cancer;   Stage IV Primary Peritoneal Cavity Cancer
Interventions: Other: pharmacological study;   Other: questionnaire administration;   Procedure: assessment of therapy complications;   Other: quality-of-life assessment;   Drug: carboplatin;   Drug: paclitaxel;   Biological: filgrastim
38 Completed OVATURE (OVArian TUmor REsponse) A Phase III Study of Weekly Carboplatin With and Without Phenoxodiol in Patients With Platinum-Resistant, Recurrent Epithelial Ovarian Cancer
Conditions: Fallopian Tube Cancer;   Peritoneal Neoplasms;   Ovarian Cancer
Interventions: Drug: phenoxodiol;   Drug: carboplatin
39 Active, not recruiting A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer
Condition: Breast Cancer
Interventions: Drug: metformin hydrochloride;   Other: placebo
40 Active, not recruiting 3'-Deoxy-3'-18F Fluorothymidine PET/CT Scanning in Patients Undergoing Treatment for Stage III Breast Cancer
Conditions: Recurrent Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Drug: fluorine F 18 fluorothymidine;   Procedure: positron emission tomography;   Procedure: computed tomography;   Other: laboratory biomarker analysis

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