52 studies found for:    brain tumor AND pediatrics | "Brain Stem Glioma, Childhood"
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Rank Status Study
1 Completed Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors
Conditions: Childhood Central Nervous System Germ Cell Tumor;   Childhood Choroid Plexus Tumor;   Childhood Craniopharyngioma;   Childhood Ependymoblastoma;   Childhood Grade I Meningioma;   Childhood Grade II Meningioma;   Childhood Grade III Meningioma;   Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Medulloepithelioma;   Childhood Mixed Glioma;   Childhood Oligodendroglioma;   Childhood Supratentorial Ependymoma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Pineoblastoma;   Recurrent Childhood Subependymal Giant Cell Astrocytoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma
Interventions: Drug: O6-benzylguanine;   Drug: temozolomide;   Biological: filgrastim;   Other: pharmacological study;   Other: laboratory biomarker analysis
2 Recruiting Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors
Conditions: Recurrent Childhood Anaplastic Astrocytoma;   Recurrent Childhood Anaplastic Ependymoma;   Recurrent Childhood Diffuse Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Giant Cell Glioblastoma;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Gliosarcoma;   Recurrent Childhood Oligodendroglioma;   Recurrent Childhood Brain Stem Glioma
Interventions: Drug: imetelstat sodium;   Other: laboratory biomarker analysis;   Other: pharmacological study
3 Recruiting p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor;   Childhood Choroid Plexus Tumor;   Recurrent Childhood Anaplastic Astrocytoma;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Giant Cell Glioblastoma;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Gliosarcoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions: Drug: azurin-derived cell-penetrating peptide p28;   Other: laboratory biomarker analysis;   Other: pharmacological study
4 Completed
Has Results
Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed Gliomas
Conditions: Untreated Childhood Anaplastic Astrocytoma;   Untreated Childhood Anaplastic Oligodendroglioma;   Untreated Childhood Brain Stem Glioma;   Untreated Childhood Giant Cell Glioblastoma;   Untreated Childhood Glioblastoma;   Untreated Childhood Gliomatosis Cerebri;   Untreated Childhood Gliosarcoma;   Untreated Childhood Oligodendroglioma
Interventions: Drug: gefitinib;   Radiation: radiation therapy;   Other: pharmacological study;   Other: laboratory biomarker analysis
5 Completed Cilengitide in Treating Children With Refractory Primary Brain Tumors
Conditions: Childhood Central Nervous System Germ Cell Tumor;   Childhood Choroid Plexus Tumor;   Childhood Craniopharyngioma;   Childhood Ependymoblastoma;   Childhood Grade I Meningioma;   Childhood Grade II Meningioma;   Childhood Grade III Meningioma;   Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Medulloepithelioma;   Childhood Mixed Glioma;   Childhood Oligodendroglioma;   Childhood Supratentorial Ependymoma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Brain Tumor;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Pineoblastoma;   Recurrent Childhood Subependymal Giant Cell Astrocytoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma
Interventions: Drug: cilengitide;   Other: laboratory biomarker analysis
6 Completed Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma
Conditions: Childhood Burkitt Lymphoma;   Childhood Central Nervous System Germ Cell Tumor;   Childhood Choroid Plexus Tumor;   Childhood Craniopharyngioma;   Childhood Grade I Meningioma;   Childhood Grade II Meningioma;   Childhood Grade III Meningioma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Spinal Cord Neoplasm;   Childhood Supratentorial Ependymoma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Brain Tumor;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Grade III Lymphomatoid Granulomatosis;   Recurrent Childhood Large Cell Lymphoma;   Recurrent Childhood Lymphoblastic Lymphoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Small Noncleaved Cell Lymphoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: ispinesib;   Other: laboratory biomarker analysis;   Other: pharmacological study
7 Completed ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor;   Childhood Central Nervous System Germ Cell Tumor;   Childhood Choroid Plexus Tumor;   Childhood Craniopharyngioma;   Childhood Ependymoblastoma;   Childhood Grade I Meningioma;   Childhood Grade II Meningioma;   Childhood Grade III Meningioma;   Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Medulloepithelioma;   Childhood Mixed Glioma;   Childhood Oligodendroglioma;   Childhood Supratentorial Ependymoma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Brain Tumor;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Pineoblastoma;   Recurrent Childhood Spinal Cord Neoplasm;   Recurrent Childhood Subependymal Giant Cell Astrocytoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma
Interventions: Drug: veliparib;   Drug: temozolomide;   Other: pharmacological study;   Other: laboratory biomarker analysis
8 Active, not recruiting AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor;   Childhood Central Nervous System Germ Cell Tumor;   Childhood Grade I Meningioma;   Childhood Grade II Meningioma;   Childhood Grade III Meningioma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Oligodendroglioma;   Childhood Spinal Cord Neoplasm;   Childhood Supratentorial Ependymoma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Brain Tumor;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Pineoblastoma;   Recurrent Childhood Subependymal Giant Cell Astrocytoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma
Intervention: Drug: cediranib maleate
9 Completed
Has Results
Tipifarnib and Radiation Therapy in Treating Young Patients With Brainstem Glioma
Condition: Untreated Childhood Brain Stem Glioma
Interventions: Radiation: radiation therapy;   Drug: tipifarnib
10 Completed
Has Results
Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors
Conditions: Recurrent Childhood Anaplastic Astrocytoma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Giant Cell Glioblastoma;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Gliosarcoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Oligodendroglioma
Interventions: Drug: lapatinib ditosylate;   Procedure: therapeutic conventional surgery;   Other: laboratory biomarker analysis;   Other: pharmacological study;   Procedure: positron emission tomography;   Procedure: magnetic resonance imaging
11 Completed Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors
Conditions: Childhood Soft Tissue Sarcoma;   Childhood Liver Cancer;   Bone Cancer;   Brain Tumor;   Kidney Tumor
Intervention: Drug: doxorubicin HCl liposome
12 Completed Phenylacetate in Treating Children With Recurrent or Progressive Brain Tumors
Condition: Brain and Central Nervous System Tumors
Intervention: Drug: phenylacetate
13 Recruiting Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas
Condition: Pediatric High Risk Gliomas
Intervention: Drug: Combination of two marketed drugs (irinotecan and cisplatin)
14 Unknown  Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors
Conditions: Bone Marrow Suppression;   Brain and Central Nervous System Tumors;   Drug/Agent Toxicity by Tissue/Organ
Interventions: Procedure: filgrastim;   Biological: gene therapy;   Drug: lomustine;   Drug: procarbazine hydrochloride;   Drug: vincristine sulfate;   Procedure: in vitro-treated peripheral blood stem cell transplantation
15 Active, not recruiting
Has Results
Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma
Conditions: Childhood High-grade Cerebral Astrocytoma;   Childhood Oligodendroglioma;   Childhood Spinal Cord Neoplasm;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma
Interventions: Biological: bevacizumab;   Drug: irinotecan hydrochloride;   Radiation: fludeoxyglucose F 18
16 Completed Thalomid and Carboplatin for the Treatment of Pediatric Brain Stem Glioma
Conditions: Brain Stem Neoplasms, Primary;   Neoplasms, Brain Stem
Interventions: Drug: Carboplatin;   Drug: Thalomid;   Procedure: External Beam Radiation Therapy
17 Recruiting Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
Conditions: Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Mixed Glioma;   Childhood Pilocytic Astrocytoma;   Neurofibromatosis Type 1;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Oligodendroglioma;   Recurrent Childhood Pilocytic Astrocytoma;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Recurrent Childhood Visual Pathway Glioma
Interventions: Drug: selumetinib;   Other: laboratory biomarker analysis;   Other: pharmacological study
18 Active, not recruiting
Has Results
Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
Conditions: Brain and Central Nervous System Tumors;   Cognitive/Functional Effects;   Long-term Effects Secondary to Cancer Therapy in Children;   Neurotoxicity;   Psychosocial Effects of Cancer and Its Treatment;   Radiation Toxicity
Intervention: Drug: Donepezil
19 Completed Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors
Conditions: Brain and Central Nervous System Tumors;   Childhood Germ Cell Tumor;   Kidney Cancer;   Liver Cancer;   Neuroblastoma;   Ovarian Cancer;   Sarcoma;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: carboplatin;   Drug: talabostat mesylate;   Drug: temozolomide;   Other: pharmacological study
20 Suspended PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors
Condition: Brain and Central Nervous System Tumors
Intervention: Drug: VEGF inhibitor PTC299

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Indicates status has not been verified in more than two years