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30 studies found for:    Tuberous Sclerosis

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Tuberous Sclerosis (30 records)
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Rank Status Study
1 Recruiting Early Biomarkers of Autism in Infants With Tuberous Sclerosis Complex (TSC)
Condition: Tuberous Sclerosis Complex
Intervention:
2 Recruiting Study of Skin Tumors in Tuberous Sclerosis
Conditions: Hereditary Neoplastic Syndrome;   Tuberous Sclerosis
Intervention:
3 Active, not recruiting
Has Results 		Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)
Conditions: Tuberous Sclerosis;   Subependymal Giant Cell Astrocytoma
Interventions: Drug: Everolimus;   Drug: Placebo
4 Completed Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM
Conditions: Tuberous Sclerosis;   Lymphangioleiomyomatosis
Intervention: Drug: Rapamycin, sirolimus
5 Recruiting Tuberous Sclerosis Complex Natural History Study: Renal Manifestations
Condition: Tuberous Sclerosis Complex
Intervention:
6 Active, not recruiting Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex
Conditions: Tuberous Sclerosis;   Subependymal Giant Cell Astrocytoma
Intervention: Drug: Everolimus
7 Recruiting Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC)
Condition: Tuberous Sclerosis Complex
Intervention: Drug: RAD001
8 Completed Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)
Conditions: Tuberous Sclerosis;   Neurofibromatoses;   Angiofibroma;   Neurofibroma
Interventions: Drug: Skincerity;   Drug: Skincerity plus sirolimus/rapamycin;   Drug: Skinercity plus sirolimus/rapamycin
9 Active, not recruiting Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM)
Conditions: Tuberous Sclerosis;   Angiolipoma
Intervention: Drug: everolimus (RAD001)
10 Active, not recruiting Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)
Conditions: Epilepsy;   Tuberous Sclerosis Complex
Intervention: Drug: Everolimus
11 Recruiting Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex
Conditions: Tuberous Sclerosis Complex;   TSC Related Cognitive Disability;   TSC Related Autism;   TSC Related Learning Problems
Interventions: Drug: Everolimus;   Drug: Placebo
12 Active, not recruiting
Has Results 		Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)
Conditions: Tuberous Sclerosis Complex (TSC);   Lymphangioleiomyomatosis (LAM)
Interventions: Drug: Everolimus (RAD001);   Other: Placebo
13 Unknown † Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM
Conditions: Tuberous Sclerosis;   Lymphangioleiomyomatosis
Intervention: Drug: sirolimus
14 Recruiting A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures
Condition: Tuberous Sclerosis Complex-associated Refractory Seizures
Interventions: Drug: RAD001;   Drug: Placebo
15 Active, not recruiting RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM
Conditions: Tuberous Sclerosis;   Lymphangioleiomyomatosis
Intervention: Drug: RAD001
16 Recruiting Sabril for Complex Partial Seizures in Adult Tolerability Study (TS) Patients
Condition: Complex Partial Seizures
Intervention: Drug: vigabatrin
17 Completed Studies of Autistic Patients: Gene Networks and Clinical Subtypes
Conditions: Autism;   Tuberous Sclerosis
Intervention:
18 Not yet recruiting Tuberous Sclerosis Complex: Facial Angiofibroma Skin Cream
Condition: Facial Angiofibroma
Intervention: Drug: Rapamune
19 Recruiting Potential EEG Biomarkers and Antiepileptogenic Strategies for Epilepsy in TSC
Condition: Tuberous Sclerosis Complex
Intervention:
20 Recruiting Topical Rapamycin to Erase Angiofibromas in TSC
Conditions: Angiofibromas;   Tuberous Sclerosis
Interventions: Drug: Placebo;   Drug: Rapamycin
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† Indicates status has not been verified in more than two years