12 studies found for:    RO4917523
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Study Details
Participant Details
Identifiers
Dates
Rank Status Study
1 Completed A Study of The Excretion Balance, Pharmacokinetics and Metabolism of A Single Oral Dose of [14C]-Labeled RO4917523 in Healthy Male Volunteers
Condition: Healthy Volunteer
Intervention: Drug: RO4917523
2 Completed A Study of RO4917523 in Pediatric Patients With Fragile X Syndrome
Condition: Fragile X Syndrome
Interventions: Drug: Placebo;   Drug: RO4917523
3 Completed A Study of RO4917523 in Patients With Fragile X Syndrome
Condition: Fragile X Syndrome
Interventions: Drug: Placebo;   Drug: RO4917523
4 Completed A Study With RO4917523 in Patients With Fragile X Syndrome
Condition: Fragile X Syndrome
Interventions: Drug: Placebo;   Drug: RO4917523
5 Completed MARIGOLD Study: A Study of RO4917523 Versus Placebo as Adjunctive Therapy in Patients With Major Depressive Disorder and an Inadequate Response to Ongoing Antidepressant Therapy
Condition: Depression Disorder, Major
Interventions: Drug: Placebo;   Drug: RO4917523
6 Completed A Human Proof of Concept Study for [11C]-RO5011232 as Radiotracer and Study of the Binding of RO4917523 to Human mGlu5 Brain Receptor at Steady-State in Healthy Volunteers
Condition: Healthy Volunteer
Interventions: Drug: RO4917523;   Drug: RO5011232
7 Completed A Study of the Effect of Fluvoxamine on the Pharmacokinetics of RO4917523 in Healthy Volunteers
Condition: Healthy Volunteer
Interventions: Drug: Fluvoxamine;   Drug: RO4917523
8 Completed A Study of the Effect of Carbamazepine on the Pharmacokinetics of RO4917523 in Healthy Volunteers
Condition: Healthy Volunteer
Interventions: Drug: Carbamazepine;   Drug: RO4917523
9 Completed A Study of Three Modified-Release Formulations of RO4917523 in Healthy Volunteers
Condition: Healthy Volunteer
Intervention: Drug: RO4917523
10 Completed A Pharmacokinetic Study of RO4917523 in Healthy Japanese and Caucasian Subjects
Condition: Healthy Volunteer
Interventions: Drug: placebo;   Drug: RO4917523
11 Completed A Study of RO4917523 in Patients With Treatment Resistant Depression
Condition: Depression
Interventions: Drug: RO4917523;   Drug: Placebo
12 Completed A Study of the Ability of Functional Magnetic Resonance Imaging (fMRI) to Detect and Characterize the Effects of Two Marketed Centrally Active Drugs, Placebo, and RO4917523 in Healthy Volunteers
Condition: Healthy Volunteer
Interventions: Drug: escitalopram;   Drug: methylphenidate;   Drug: RO4917523;   Drug: placebo

Indicates status has not been verified in more than two years