195 studies found for:    Primary Lateral Sclerosis
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Rank Status Study
21 Completed Safety Extension Study of TRO19622 in ALS
Condition: Amyotrophic Lateral Sclerosis
Intervention: Drug: TRO19622
22 Recruiting Impact of Early Non Invasive Ventilation in Amyotrophic Lateral Sclerosis (ALS) Patients
Condition: Amyotrophic Lateral Sclerosis
Intervention: Device: Home pressure ventilator model Vivo 40 (BREAS Medical AB)
23 Terminated
Has Results
Study to Investigate the Safety and Efficacy of Lithium in Volunteers With Amyotrophic Lateral Sclerosis (ALS)
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: Lithium Carbonate;   Drug: Riluzole;   Drug: placebo
24 Completed Exogenous Toxicants and Genetic Susceptibility in ALS
Condition: Amyotrophic Lateral Sclerosis
Intervention:
25 Terminated Study of Pioglitazone in Patients With Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: pioglitazone;   Drug: placebo
26 Active, not recruiting Dysfunctions and Plasticity Mechanisms of Motor System Assessed by Cortico-cortical and Cortico-muscular Coherence Analysis in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Procedure: electroencephalograms (EEG);   Procedure: electro-myography (EMG)
27 Terminated Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Conditions: Frontotemporal Dementia;   Amyotrophic Lateral Sclerosis
Intervention:
28 Unknown  Polysomnography-directed Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS)
Condition: Amyotrophic Lateral Sclerosis (ALS)
Interventions: Other: Sleep study-guided adjustment of NIV;   Other: Standard initiation of NIV
29 Unknown  Efficacy and Tolerability of Tauroursodeoxycholic Acid in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: tauroursodeoxycholic acid (TUDCA);   Drug: Placebo
30 Recruiting Non-invasive Ventilation in Amyotrophic Lateral Sclerosis (ALS) Using the iVAPS Mode
Condition: Amyotrophic Lateral Sclerosis (ALS)
Intervention: Device: Non-invasive home ventilation
31 Completed CARE Canadian ALS Riluzole Evaluation
Condition: Amyotrophic Lateral Sclerosis
Intervention: Drug: Riluzole
32 Recruiting Influence of the Vitamin D Blood Levels on the Amyotrophic Lateral Sclerosis Phenotype
Condition: Amyotrophic Lateral Sclerosis
Intervention: Procedure: Blood test
33 Recruiting Natural History and Biomarkers of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Caused by the C9ORF72 Gene Mutation
Condition: Amyotrophic Lateral Sclerosis
Intervention:
34 Active, not recruiting Study of Ozanezumab (GSK1223249) Versus Placebo in the Treatment of Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: Ozanezumab;   Drug: Placebo
35 Completed
Has Results
Clinical Trial of High Dose CoQ10 in ALS
Conditions: Amyotrophic Lateral Sclerosis;   Lou Gehrig's Disease
Interventions: Drug: coenzyme Q10;   Drug: Placebo
36 Active, not recruiting GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)
Condition: Amyotrophic Lateral Sclerosis
Intervention: Drug: GM604
37 Recruiting From Movement Preparation to Gait Execution in ALS
Condition: Amyotrophic Lateral Sclerosis
Intervention:
38 Enrolling by invitation Muscle Training of Patients With Amyotrophic Lateral Sclerosis (ALS)
Condition: Amyotrophic Lateral Sclerosis
Intervention: Other: Muscle training
39 Recruiting Innovative Measures of Speech and Swallowing Dysfunction in Neurological Disorders
Conditions: Amyotrophic Lateral Sclerosis (ALS);   Myasthenia Gravis;   Myopathies;   Stroke;   Parkinson's Disease
Intervention:
40 Unknown  Nocturnal PtcCO2 Monitoring in Patients With Amyotrophic Lateral Sclerosis (ALS)
Condition: Amyotrophic Lateral Sclerosis
Intervention: Device: PtcCO2

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Indicates status has not been verified in more than two years