50 studies found for:    Periventricular Leukomalacia
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Rank Status Study
1 Completed Neuroprotection by Magnesium Sulfate Given to Women at Risk of Very Preterm Birth
Conditions: Preterm Birth;   Periventricular Leukomalacia;   Brain Ischemia;   Intracranial Hemorrhages
Intervention: Drug: magnesium
2 Terminated Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity
Conditions: Bacterial Vaginosis;   Premature Birth;   Sepsis;   Periventricular Leukomalacia;   Bronchopulmonary Dysplasia
Intervention: Drug: Lactobacillus rhamnosus GR1 and Lactobacillus reuteri RC-14
3 Completed Premature Infants in Need of Transfusion (PINT)
Condition: Anemia of Prematurity
Intervention: Procedure: Red blood cell transfusion
4 Unknown  Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants
Conditions: Infant, Premature;   Leukomalacia, Periventricular;   Intraventricular Hemorrhage;   Retinopathy of Prematurity
Interventions: Drug: recombinant human erythropoietin (rhEpo);   Drug: Normal saline
5 Terminated High-Dose Erythropoietin in Extremely Premature Infants to Prevent/Attenuate Brain Injury: A Phase II Study
Conditions: Infant, Premature;   Erythropoietin;   Brain Injury;   Intraventricular Hemorrhage;   Periventricular Leukomalacia;   Neurodevelopmental Outcomes;   Randomized Clinical Trial
Interventions: Drug: Erythropoietin;   Drug: Saline placebo
6 Recruiting Inhaled Nitric Oxide and Neuroprotection in Premature Infants
Conditions: Prematurity;   Bronchopulmonary Dysplasia;   Intraventricular Hemorrhage;   Periventricular Leukomalacia
Interventions: Drug: inhaled nitric oxide;   Drug: oxygen
7 Recruiting Physiological Disturbances Associated With Neonatal Intraventricular Hemorrhage
Conditions: Intraventricular Hemorrhage;   Autoregulation
Interventions: Other: Hypercapnia;   Other: Normocapnia
8 Completed Antenatal Phenobarbital to Prevent Neonatal Intracranial Hemorrhage
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Intracranial Hemorrhages
Interventions: Drug: Phenobarbital;   Drug: Saline
9 Recruiting S100B as a Marker of Brain Injury of Preterm Infants
Conditions: Premature Birth;   Brain Injuries;   Leukomalacia Periventricular;   Developmental Disabilities
Intervention:
10 Completed
Has Results
17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies
Condition: Preterm Birth
Interventions: Drug: 17-alpha-hydroxyprogesterone caproate injectable;   Drug: Placebo
11 Completed Umbilical Cord Blood Proteomic Analysis and Neonatal Brain Injury
Conditions: Hypoxia-Ischemia, Brain;   Periventricular Leukomalacia;   Umbilical Cord Blood;   Proteomics
Intervention:
12 Completed Does Erythropoietin Improve Outcome in Very Preterm Infants?
Conditions: Intracranial Hemorrhage;   Periventricular Leukomalacia;   Postnatal Development;   Cerebral Palsy
Intervention: Drug: Recombinant human Erythropoietin
13 Completed Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial)
Conditions: Cerebral Palsy;   Intraventricular Hemorrhage;   Periventricular Leukomalacia;   Pulmonary Edema;   Abruptio Placentae
Intervention: Drug: magnesium sulfate
14 Terminated
Has Results
Feasibility Study of Aerosolized Surfaxin in the Prevention of Respiratory Distress Syndrome (RDS) in Premature Infants
Condition: Respiratory Distress Syndrome
Intervention: Drug: Aerosolized lucinactant
15 Not yet recruiting Management of Hypotension In the Preterm Infant
Conditions: Hypotension;   Low Blood Pressure;   Intraventricular Hemorrhage of Prematurity
Interventions: Drug: Dopamine hydrochloride;   Drug: Dextrose 5%
16 Completed Optic Discs in Children With Cerebral Palsy
Condition: Cerebral Palsy
Intervention:
17 Unknown  Magnesium Sulfate to Prevent Brain Injury in Premature Infants
Conditions: Brain Injuries;   Cerebral Palsy
Intervention: Drug: magnesium sulfate
18 Completed Liberal Versus Restrictive Transfusion Guidelines for Preterm Infants
Conditions: Infant, Premature;   Anemia;   Intracranial Hemorrhages;   Leukomalacia, Periventricular;   Apnea
Intervention: Procedure: Red blood cell transfusion guidelines
19 Completed Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in High Risk Pregnancies
Condition: Preterm Birth
Intervention: Drug: 17 alpha-Hydroxyprogesterone Caproate and Omega-3 fish oils
20 Completed Safety and Efficacy Study of Ibuprofen l-Lysine Solution in Premature Infants for Treatment of PDA
Condition: Patent Ductus Arteriosus
Intervention: Drug: ibuprofen l-lysine iv solution (NeoProfen (R) )

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Indicates status has not been verified in more than two years