587 studies found for:    Neurotoxicity
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Rank Status Study
1 Completed
Has Results
Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery
Conditions: Colorectal Cancer;   Neurotoxicity
Interventions: Drug: calcium gluconate;   Drug: magnesium sulfate;   Other: placebo
2 Active, not recruiting Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy
Conditions: Chemotherapeutic Agent Toxicity;   Colorectal Cancer;   Neuropathy;   Neurotoxicity
Interventions: Drug: calcium gluconate;   Drug: magnesium sulfate;   Other: placebo
3 Active, not recruiting Monosialotetrahexosylganglioside Sodium Injection for Prevention Neurotoxicity of mFOLFOX 6 in mCRC
Condition: Colorectal Cancer
Interventions: Drug: monosialotetrahexosylganglioside Sodium;   Other: placebo
4 Active, not recruiting Monosialotetrahexosylganglioside Sodium Injection for Prevention Neurotoxicity of mFOLFOX 6 in Advanced Gastric Cancer
Condition: Gastric Cancer
Interventions: Drug: monosialotetrahexosylganglioside Sodium;   Other: placebo
5 Unknown  Biomarkers in Predicting Neurotoxicity in Patients With Colorectal Cancer Receiving Oxaliplatin
Conditions: Chemotherapeutic Agent Toxicity;   Colorectal Cancer;   Neurotoxicity
Interventions: Drug: FOLFOX regimen;   Drug: fluorouracil;   Drug: leucovorin calcium;   Drug: oxaliplatin;   Genetic: gene expression analysis;   Genetic: protein expression analysis;   Genetic: proteomic profiling;   Other: laboratory biomarker analysis;   Other: pharmacogenomic studies
6 Recruiting Monosialoganglioside(GM1) Preventing Neurotoxicity Induced by Cisplatin Contained Chemotherapy in NSCLC Patients
Condition: Non-small Cell Lung Cancer
Interventions: Drug: Monosialoganglioside(GM1);   Drug: normal saline
7 Terminated A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate Neurotoxicity
Condition: Neurotoxicity Syndromes
Intervention: Drug: Dextromethorphan
8 Recruiting Neurotoxicity Characterization Study of Nab-paclitaxel Versus Conventional Paclitaxel in Metastatic Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Paclitaxel 80 mg/m2;   Drug: Nab-paclitaxel 100 mg/m2 days 1, 8 and 15;   Drug: Nab-paclitaxel 150 mg/m2 days 1, 8 and 15;   Drug: Nab-paclitaxel 150 mg/m2 days 1 and 15
9 Unknown  Relationship Between Platinum Levels in the Blood and Neurotoxicity in Patients Who Are Receiving Oxaliplatin for Gastrointestinal Cancer
Condition: Cancer
Interventions: Drug: oxaliplatin;   Procedure: management of therapy complications
10 Active, not recruiting Evaluation of BNP7787 for the Prevention of Neurotoxicity in Metastatic Breast Cancer Patients Receiving Weekly Paclitaxel
Conditions: Breast Neoplasms;   Breast Diseases;   Metastases, Neoplasm
Interventions: Drug: BNP7787;   Drug: Placebo
11 Completed Use of FACT-GOG/NTX Questionnaire in Peripheral Neurotoxicity & Validation of a French Version of This Questionnaire
Conditions: Ovarian Cancer;   Fallopian Tube Cancer;   Peritoneal Neoplasms
Interventions: Drug: Paclitaxel;   Drug: EPO
12 Completed Protective Effect of Mangafodipir Against Oxaliplatin Neurotoxicity
Conditions: Neurotoxic Disorders;   Cancer
Intervention: Drug: Mangafodipir
13 Completed
Has Results
Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer
Conditions: Kidney Cancer;   Leukemia;   Lymphoma;   Neurotoxicity;   Peripheral Neuropathy;   Sarcoma
Interventions: Drug: glutamic acid;   Other: placebo
14 Recruiting Study to Assess Prevention of Oxaliplatin-induced Neurotoxicity Through Vitamin D Pathway
Condition: Neurotoxicity
Intervention: Drug: Vitamin D3
15 Recruiting Heavy Metal Exposure in Predicting Peripheral Neuropathy in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy
Conditions: Male Breast Cancer;   Neurotoxicity;   Peripheral Neuropathy;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Other: laboratory biomarker analysis;   Other: questionnaire administration
16 Completed XENOX – Evaluation of the Efficacy of Xaliproden in Reducing the Neurotoxicity of the Oxaliplatin + 5-FU/LV Chemotherapy
Conditions: Metastases;   Colorectal Neoplasms;   Colorectal Carcinoma
Intervention: Drug: SR57746A
17 Completed Evaluation of the Efficacy of Xaliproden (SR57746A) in Preventing the Neurotoxicity of Oxaliplatin / 5FU/LV Chemotherapy.
Conditions: Metastases;   Colorectal Neoplasms;   Colorectal Carcinoma
Interventions: Drug: xaliproden (SR57746A);   Drug: Placebo;   Drug: oxaliplatin
18 Completed Oral Glutamine in the Prevention of Oxaliplatin-induced Neurotoxicity
Condition: Colorectal Neoplasms
Interventions: Drug: Glutamine;   Drug: Calcium and Magnesium
19 Completed S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, Stage II, or Stage IIIA Breast Cancer Undergoing Chemotherapy
Conditions: Breast Cancer;   Chemotherapeutic Agent Toxicity;   Fatigue;   Neuropathy;   Neurotoxicity
Interventions: Dietary Supplement: acetyl-L-carnitine hydrochloride;   Other: placebo
20 Terminated Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer
Conditions: Cervical Cancer;   Endometrial Cancer;   Fallopian Tube Cancer;   Neurotoxicity;   Ovarian Cancer;   Primary Peritoneal Cavity Cancer;   Sarcoma
Interventions: Drug: amifostine trihydrate;   Drug: cisplatin;   Drug: paclitaxel

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Indicates status has not been verified in more than two years