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28 studies found for:    Mitochondrial Myopathies

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1 Completed Pilot Compassionate Use Study of Thioctic Acid Treatment in Mitochondrial Myopathy
Condition: Mitochondrial Myopathy
Intervention: Drug: thioctic acid
2 Unknown † The Effects of Exercise Versus Inactivity on People With Mitochondrial Muscle Disease
Condition: Mitochondrial Myopathy
Intervention: Behavioral: Exercise
3 Completed Defining 31Phosphorous Magnetic Resonance Spectroscopy Characteristics in Patients With Mitochondrial Myopathy
Condition: Mitochondrial Disease
Intervention:
4 Completed Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia
Conditions: Mitochondrial Myopathy;   MELAS Syndrome;   Lactic Acidosis
Intervention:
5 Recruiting Study of Inherited Neurological Disorders
Conditions: Ataxia;   Motor Neuron Disease;   Muscular Disease;   Muscular Dystrophy;   Peripheral Nervous System Disease
Intervention:
6 Recruiting Natural History Study - Mitochondrial Disease
Condition: Mitochondrial DNA Mutation
Intervention:
7 Completed Ketones & Mitochondrial Heteroplasmy
Conditions: MELAS Syndrome;   Mitochondrial Diseases
Intervention: Dietary Supplement: Medium-Chain Triglycerides
8 Completed Responses to Influenza Vaccine in Patients With Mitochondrial Disorders (MELAS)
Condition: MELAS Syndrome
Intervention: Biological: Intramuscular seasonal trivalent inactivated influenza vaccine
9 Not yet recruiting L-arginine Therapy on Endothelium-dependent Vasodilation & Mitochondrial Metabolism in MELAS Syndrome
Condition: MELAS Syndrome
Intervention: Drug: L-Arginine
10 Active, not recruiting Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes
Condition: MELAS Syndrome
Interventions: Drug: Idebenone;   Other: Placebo
11 Unknown † Nitric Oxide Production in MELAS Syndrome
Condition: MELAS Syndrome
Intervention: Dietary Supplement: Arginine and citrulline supplementations
12 Unknown † Evaluating the Effectiveness of a Dichloroacetate in MELAS Syndrome
Condition: MELAS Syndrome
Intervention: Drug: Dichloroacetate
13 Completed The Effect of Fibrate Therapy in Two Patients With Neutral Lipid Storage Disease With Myopathy (NLSDM)
Condition: Neutral Lipid Storage Disease
Intervention: Drug: Fibrate treatment
14 Recruiting Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS
Conditions: Myopathy;   HMG COA Reductase Inhibitor Adverse Reaction;   Hypercholesterolemia
Interventions: Dietary Supplement: ubiquinol;   Dietary Supplement: placebo;   Drug: statin
15 Completed Effects of Statins on Pro- and Antioxidant Status : Link With Statin-Associated Myopathy.
Condition: Healthy
Intervention: Drug: Simvastatin
16 Active, not recruiting Low Protein Diet in Patients With Collagen VI Related Myopathies
Conditions: Bethlem Myopathy;   Ullrich Congenital Muscular Dystrophy
Intervention: Other: Low protein diet
17 Active, not recruiting Quality of Life in Patients With Statin-Associated Myopathy
Condition: Statin-Associated Myopathy
Interventions: Drug: Statins;   Drug: Lactose placebo pills
18 Not yet recruiting Early Goal-Directed Nutrition in ICU Patients - EAT-ICU Trial
Conditions: Critical Illness;   Intensive Care (ICU) Myopathy;   Muscle Wasting;   Loss of Physical Function;   Mechanical Ventilation
Interventions: Other: Early Goal-Directed Nutrition;   Other: ASPEN-guidelines
19 Withdrawn Muscle Characteristics Associated With Statin Therapy
Conditions: Hydroxymethylglutaryl-CoA Reductase Inhibitors;   Myopathy
Intervention: Drug: simvastatin
20 Active, not recruiting Effects of Parenteral L-carnitine Supplementation in Premature Neonates
Condition: Prematurity
Interventions: Drug: Parenteral L-carnitine supplementation;   Drug: Parenteral supplementation with sterile water
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† Indicates status has not been verified in more than two years