34 studies found for:    Marfan Syndrome
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Dates
Rank Status Study
1 Recruiting Aortopathy in Persons With Bicuspid Aortic Valve, Turner and Marfan Syndrome
Conditions: Turner Syndrome;   Bicuspid Aortic Valve;   Marfan Syndrome
Intervention:
2 Unknown  Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome
Condition: Marfan Syndrome
Interventions: Drug: Losartan;   Drug: Atenolol
3 Recruiting Development of a Blood Test for Marfan Syndrome
Conditions: Marfan Syndrome;   Marfan Related Disorders;   Control Subjects
Intervention:
4 Completed Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome
Condition: Marfan Syndrome
Interventions: Drug: Atenolol;   Drug: Losartan
5 Completed Clinical Variability in Marfan Syndrome
Condition: Marfan Syndrome
Interventions: Procedure: skin punch biopsy and molecular biology;   Other: fibroblast culture and molecular biology
6 Completed Angiotensin Converting Enzyme Inhibitors in Marfan Syndrome
Condition: Marfan Syndrome
Intervention: Drug: Coversyl (perindopril)
7 Terminated Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome
Condition: Marfan Syndrome
Interventions: Drug: placebo;   Drug: Losartan
8 Completed Comparison of Medical Therapies in Marfan Syndrome.
Condition: Marfan Syndrome
Interventions: Drug: Atenolol;   Drug: VERAPAMIL;   Drug: Perindopril
9 Completed Losartan Versus Atenolol for the Treatment of Marfan Syndrome
Condition: Marfan Syndrome
Interventions: Drug: Losartan;   Drug: Atenolol
10 Completed Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome--Pediatric Heart Network
Condition: Marfan Syndrome
Interventions: Drug: Losartan Potassium;   Drug: Atenolol
11 Recruiting Comparison Study of the Effect of Aliskiren Versus Negative Controls on Aortic Stiffness in Patients With Marfan Syndrome Under Treatment With Atenolol
Condition: Marfan Syndrome
Interventions: Drug: Aliskiren;   Drug: Atenolol
12 Unknown  A Randomized, Open-label, LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan Syndrome
Condition: Marfan Syndrome
Interventions: Drug: Losartan and Atenolol or Propranolol;   Drug: Atenolol or Propranolol
13 Unknown  Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients
Condition: Marfan Syndrome
Interventions: Drug: Losartan and nebivolol;   Drug: Losartan;   Drug: Nebivolol
14 Recruiting Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic Root Dilatation in Patients With Marfan Syndrome Under Treatment With Beta-blockers
Condition: Marfan Syndrome
Interventions: Drug: Losartan;   Drug: Placebo
15 Unknown  Genetic Study of the FBN1 Gene and Fibrillin-1 Abnormalities in Choctaw Native Americans and Other Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention:
16 Withdrawn Circulating Transforming Growth Factor Beta (TGF-β) in Individuals With Marfan Syndrome
Condition: Marfan Syndrome
Intervention: Other: Blood draw
17 Recruiting Thoracic Aortic Dilatation Syndromes
Conditions: Thoracic Aorta Dilatation;   Marfan Syndrome
Intervention:
18 Recruiting The Oxford Marfan Trial
Condition: Marfan Syndrome
Interventions: Drug: Irbesartan 150-300mg capsules daily for 6 months;   Drug: Doxycycline 100-200mg capsules daily for 6 months;   Drug: Doxycycline placebo capsules daily for 6 months;   Drug: Irbesartan placebo capsules daily for 6 months
19 Completed Study of Heritable Connective Tissue Disorders
Conditions: Connective Tissue Disease;   Dissecting Aneurysm;   Ehlers Danlos Syndrome;   Marfan Syndrome;   Nail Patella Syndrome
Intervention:
20 Active, not recruiting National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions
Conditions: Marfan Syndrome;   Turner Syndrome;   Ehlers-Danlos Syndrome;   Loeys-Dietz Syndrome;   FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation;   Bicuspid Aortic Valve Without Known Family History;   Bicuspid Aortic Valve With Family History;   Bicuspid Aortic Valve With Coarctation;   Familial Thoracic Aortic Aneurysm and Dissections;   Shprintzen-Goldberg Syndrome;   Other Aneur/Diss of Thoracic Aorta Not Due to Trauma, <50yo;   Other Congenital Heart Disease
Intervention:

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Indicates status has not been verified in more than two years