23 studies found for:    Lennox-Gastaut Syndrome
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Rank Status Study
1 Unknown  Melatonin Versus Placebo in the Lennox-Gastaut Syndrome: Neurophysiological and Neuropsychological Effects
Condition: Lennox-Gastaut Syndrome
Interventions: Drug: melatonin;   Drug: placebo
2 Active, not recruiting European Registry of Anti-Epileptic Drug Use in Patients With Lennox-Gastaut Syndrome (LGS)
Condition: Lennox-Gastaut Syndrome
Intervention:
3 Completed
Has Results
Safety and Effectiveness of Open-Label Clobazam in Subjects With Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome
Intervention: Drug: Clobazam
4 Completed
Has Results
A Placebo-Controlled, Double-Blind Comparative Study of E2080 in Lennox-Gastaut Syndrome Patients (Study E2080-J081-304)
Condition: Lennox-Gastaut Syndrome
Interventions: Drug: Rufinamide (E2080);   Drug: Placebo
5 Not yet recruiting An Open Label Extension Study of Cannabidiol (GWP42003-P) in Children and Young Adults With Dravet or Lennox-Gastaut Syndromes
Conditions: Epilepsy;   Dravet Syndrome;   Lennox-Gastaut Syndrome
Intervention: Drug: GWP42003-P
6 Not yet recruiting A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults
Conditions: Epilepsy;   Lennox-Gastaut Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo control
7 Not yet recruiting A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults
Conditions: Epilepsy;   Lennox-Gastaut Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo Control
8 Active, not recruiting Study of Rufinamide in Pediatric Subjects 1 to Less Than 4 Years of Age With Lennox-Gastaut Syndrome Inadequately Controlled With Other Anti-epileptic Drugs
Condition: Lennox-Gastaut Syndrome
Interventions: Drug: Rufinamide;   Drug: Any other approved AED
9 Completed Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Topiramate for Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome
Intervention: Drug: topiramate
10 Completed
Has Results
Clobazam in Patients With Lennox-Gastaut Syndrome
Conditions: Epilepsy;   Epilepsy, Generalized;   Seizures
Interventions: Drug: Clobazam Low Dose;   Drug: Clobazam Medium Dose;   Drug: Clobazam High Dose;   Drug: Placebo
11 Completed A Study of the Efficacy and Safety of Topiramate as an add-on Therapy in the Treatment of Epilepsy Patients With Lennox-Gastaut Syndrome
Conditions: Epilepsy;   Seizures
Intervention: Drug: topiramate
12 Completed
Has Results
Clobazam in Subjects With Lennox-Gastaut Syndrome
Conditions: Epilepsy;   Epilepsy, Generalized;   Seizures
Interventions: Drug: Clobazam Low Dose;   Drug: Clobazam High Dose
13 Completed Ketogenic Diet for Child Epilepsy and Seizure Control
Conditions: Epilepsy;   Seizures;   Lennox-Gastaut Syndrome
Intervention: Behavioral: Ketogenic diet
14 Completed A Study of the Safety of Topiramate Given in Combination With Other Medications in Adults and Children With Seizures
Conditions: Seizures;   Epilepsy
Intervention: Drug: Topiramate
15 Terminated
Has Results
Long-term, Open-label Safety Extension Study of Retigabine/Ezogabine in Pediatric Subjects (>= 12 Years Old) With POS or LGS
Condition: Epilepsy
Intervention: Drug: retigabine/ezogabine
16 Recruiting Post-marketing Surveillance of Long-term Administration of Inovelon Tablets in Patients With Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome
Intervention: Drug: Rufinamide
17 Active, not recruiting Epilepsy Phenome/Genome Project
Conditions: Epilepsy;   Localization-related Epilepsy;   Infantile Spasms;   Lennox-Gastaut Syndrome;   Polymicrogyria;   Periventricular Heterotopias
Intervention:
18 Completed A Long Term Extension Study of E2080 in Lennox-Gastaut Patients
Condition: Lennox-Gastaut Syndrome
Intervention: Drug: E2080
19 Terminated
Has Results
Study in Pediatric Subjects With Epilepsy
Condition: Epilepsy
Intervention: Drug: ezogabine/retigabine
20 Completed Metabolic Abnormalities in Children With Epilepsy
Conditions: Generalized Epilepsy;   Infantile Spasms;   Metabolic Disease;   Partial Epilepsy;   Seizures
Intervention: Drug: 18 FDG

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Indicates status has not been verified in more than two years