88 studies found for:    Leigh's Disease
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Rank Status Study
1 Active, not recruiting Safety and Efficacy Study of EPI-743 in Children With Leigh Syndrome
Condition: Leigh Syndrome
Interventions: Drug: Placebo;   Drug: EPI-743 15 mg/kg;   Drug: EPI-743 5 mg/kg
2 Recruiting Open-Label, Dose-Escalating Study to Assess Safety, Tolerability, Efficacy, PK and PD of RP103 in Children With Inherited Mitochondrial Disease
Condition: Inherited Mitochondrial Disease, Including Leigh Syndrome
Intervention: Drug: Cysteamine Bitartrate Delayed-release Capsules (RP103)
3 Recruiting Tissue Sample Study for Mitochondrial Disorders
Conditions: Mitochondrial Disorders;   Mitochondrial Disease;   Melas;   Kearns Sayer;   NARP;   MNGIE;   LHON;   Mitochondrial Depletion Syndrome;   Leigh's Disease
Intervention:
4 Recruiting North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
Conditions: Mitochondrial Disorders;   Mitochondrial Genetic Disorders;   Mitochondrial Diseases;   Disorder of Mitochondrial Respiratory Chain Complexes;   Deletion and Duplication of Mitochondrial DNA
Intervention:
5 Active, not recruiting EPI-743 for Mitochondrial Respiratory Chain Diseases
Condition: Mitochondrial Diseases
Intervention: Drug: EPI-743
6 Not yet recruiting Effect of Dietary Salicylate in Aspirin Exacerbated Respiratory Disease
Conditions: Chronic Rhinosinusitis;   Aspirin Exacerbated Respiratory Disease;   Asthma;   Aspirin Sensitivity
Intervention: Behavioral: Low salicylate diet
7 Completed Stalevo in Early Wearing-Off Patients
Condition: Idiopathic Parkinson's Disease
Interventions: Drug: Stalevo (levodopa/carbidopa/entacapone);   Drug: Levodopa/carbidopa
8 Completed Determination of a Questionnaire After Treatment With Pantoprazole at Full Dose and Half Dose in Adult Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/UK-506)
Conditions: Gastroesophageal Reflux;   GERD;   GORD
Intervention: Drug: Pantoprazole
9 Recruiting A Study To Investigate Safety And Efficacy Of CP-690,550 For Induction Therapy In Subjects With Moderate To Severe Crohn's Disease
Condition: Crohn's Disease
Interventions: Drug: Placebo;   Drug: CP-690,550
10 Completed
Has Results
Atomoxetine and Huntington's Disease
Conditions: Huntington Disease;   Chorea
Interventions: Drug: atomoxetine;   Drug: Matching Placebo
11 Completed
Has Results
Citalopram to Enhance Cognition in HD
Conditions: Huntington Disease;   Chorea;   Executive Dysfunction
Interventions: Drug: 20mg daily citalopram;   Drug: Placebo
12 Completed Determine Long-Term Safety and Tolerability of Pregabalin in Patients With Anxiety Disorders.
Condition: Anxiety Neuroses
Intervention: Drug: Pregabalin
13 Active, not recruiting A Study to Assess the Efficacy and Safety of Enteric-Coated Acetylsalicylic Acid in Patients at Moderate Risk of Cardiovascular Disease
Condition: Moderate Risk of CVD
Interventions: Drug: Aspirin (Acetylsalicylic acid, BAYE4465);   Drug: Placebo
14 Completed A Study to Evaluate ALKS 5461 in Subjects With Major Depressive Disorder (MDD)
Condition: Major Depressive Disorder
Interventions: Drug: ALKS 5461;   Drug: Placebo
15 Completed Providing Resources to Enhance African American Patients' Readiness to Make Decisions About Kidney Disease (PREPARED) Study
Conditions: End Stage Renal Disease (ESRD);   Chronic Kidney Disease (CKD)
Intervention: Behavioral: Information
16 Completed ALK33BUP-201: Safety and Tolerability Study of ALKS 33-BUP (ALKS 5461) Administration in Subjects With MDD
Condition: Major Depressive Disorder
Interventions: Drug: ALKS 5461;   Drug: Placebo
17 Not yet recruiting Long-Chain Fatty Acid Oxidation Disorders (LC-FAOD) Extension Study for Subjects Previously Enrolled in Triheptanoin Studies.
Conditions: Carnitine Palmitoyltransferase (CPT I or CPT II) Deficiency;   Very Long Chain Acyl-CoA Dehydrogenase (VLCAD) Deficiency;   Long-chain 3-hydroxy-acyl-CoA Dehydrogenase (LCHAD) Deficiency;   Trifunctional Protein (TFP) Deficiency;   Carnitine-acylcarnitine Translocase (CACT) Deficiency
Intervention: Drug: UX007
18 Active, not recruiting Long-term Lung Function and Disease Progression in Children With Early Onset Primary Ciliary Dyskinesia Lung Disease
Condition: Kartagener Syndrome
Intervention:
19 Recruiting BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia
Conditions: Tetraplegia;   Spinal Cord Injuries;   Amyotrophic Lateral Sclerosis;   Brain Stem Infarctions;   Locked in Syndrome
Intervention: Device: Placement of the BrainGate2 sensor into the motor cortex
20 Recruiting Longitudinal Surveillance Registry (LSR) of ACUITY Spiral
Condition: Heart Failure
Intervention: Device: ACUITY Spiral Left Ventricular Lead

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Indicates status has not been verified in more than two years